103890-70-6Relevant articles and documents
Terpyridinebenzaldehyde isomers: One-pot facile synthesis
Jouaiti, Abdelaziz
, p. 1547 - 1555 (2021)
We have explored the use of (diethoxymethyl)benzaldehyde readily available as a starting material allowing us to end up with Terpyridinebenzaldehyde isomers. An environmentally friendly procedure was undertaken for the synthesis of a series of 4, 3 and 2-([2,2′:6′,2″-terpyridin]-4′-yl)benzaldehyde isomers (para, meta and ortho position). These compounds have been synthesized in one-pot conditions using ethanol and aqueous ammonia as solvents, at room temperature. This methodology offers substantial advantages with respect to its simplicity of operation, reaction time, satisfying yield of products and easy work-up procedure under mild reaction conditions. Apart from spectroscopic characterization, the structure of one of the Terpyridinebenzaldehyde derivative is confirmed by single-crystal X-ray diffraction.
Copper-Catalyzed One-Pot Cascade Cyclization for the Synthesis of Isoindolo[2,1-a]quinoxalines
Li, Ling,Liu, Zhen-Ting,Hu, Xiang-Ping
, p. 4272 - 4276 (2021/08/03)
A copper-catalyzed one-pot cascade cyclization of 2-(1-(acetyloxy)propargyl)benzaldehydes with o-phenylenediamines for an access to substituted isoindolo[2,1-a]quinoxalines has been developed. The reaction features readily available starting materials, simple operational procedure, and broad substrate scopes. Under optimal conditions, various isoindolo[2,1-a]quinoxalines were afforded in 41–88% yields. (Figure presented.).
Asymmetric Synthesis of Multifunctionalized 2,3-Benzodiazepines by a One-Pot N-heterocyclic Carbene/Chiral Palladium Sequential Catalysis
Cheng, Ying,Ding, Ya-Li,Niu, Shuang-Shuo,Wu, Pei,Zhao, Yun-Long
, (2019/12/30)
We report the first example of the construction of chiral 2,3-benzodiazepine compounds which are of biologic and pharmaceutical relevance by asymmetric catalysis. Catalyzed by a thiazolium-derived carbene and a palladium-chiral bidentate phosphine complex
