2-(Diethoxymethyl)benzaldehyde

Base Information

• Chemical Name: 2-(Diethoxymethyl)benzaldehyde
• CAS No.: 103890-70-6
• Molecular Formula: C12H16 O3
• Molecular Weight: 208.257
• DSSTox Substance ID: DTXSID90544842
• Nikkaji Number: J1.992.859D
• Wikidata: Q82422129
• Mol file: 103890-70-6.mol

Synonyms:2-(DIETHOXYMETHYL)BENZALDEHYDE;103890-70-6;Benzaldehyde,2-(diethoxymethyl)-;2-Diethoxymethylbenzaldehyde;2-formylbenzaldehyde diethylacetal;SCHEMBL2049051;DTXSID90544842;HHYOOLILMDESPS-UHFFFAOYSA-N;MFCD11553567;AKOS015889082

Chemical Property of 2-(Diethoxymethyl)benzaldehyde

Chemical Property:

• PSA: 35.53000
• LogP: 2.57070
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 208.109944368
• Heavy Atom Count: 15
• Complexity: 176

Purity/Quality:

99.0%min ^*data from raw suppliers

2-Diethoxymethylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C1=CC=CC=C1C=O)OCC

Technology Process of 2-(Diethoxymethyl)benzaldehyde

There total 5 articles about 2-(Diethoxymethyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-bromobenzaldehyde diethyl acetal (35822-58-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-(diethoxymethyl)benzaldehyde (103890-70-6)

Guidance literature:

2-bromobenzaldehyde diethyl acetal; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 0.5h; Inert atmosphere;

N,N-dimethyl-formamide; at -70 - 20 ℃;

DOI:10.1021/jo902540x

Reference yield:

2-bromobenzaldehyde diethyl acetal (35822-58-3) → 2-(diethoxymethyl)benzaldehyde (103890-70-6)

Guidance literature:

With n-butyllithium; In N-methyl-acetamide; diethyl ether; water;

Reference yield:

Methamphetamin (537-46-2) + 2-bromobenzaldehyde diethyl acetal (35822-58-3) → 2-(diethoxymethyl)benzaldehyde (103890-70-6)

Guidance literature:

With n-butyllithium; ammonium chloride;

upstream raw materials:

orthoformic acid triethyl ester

o-phthalic dicarboxaldehyde

2-bromobenzaldehyde diethyl acetal

N,N-dimethyl-formamide

Downstream raw materials:

5-[1-(2-Diethoxymethyl-phenyl)-meth-(E)-ylidene]-imidazolidine-2,4-dione

isoquinoline-3(S)-carboxamide

(E)-2-(3-(2-bromophenyl)-3-oxoprop-1-en-1-yl)benzaldehyde

C₁₄H₂₀O₃