103897-58-1Relevant academic research and scientific papers
REACTION OF SCHIFF BASES ANIONS WITH α,ω-DIHALOALKENES : SYNTHETIC ROUTE TO CYCLIC α-AMINOACID DERIVATIVES.
Joucla, M.,Goumzili El, M.
, p. 1681 - 1684 (2007/10/02)
Imine anions of α-aminoesters, obtained from LDA/THF, undergo copper-catalyzed substitution reactions with α,ω-dihaloalkanes to lead to ω-haloalkylimines which are converted to cyclic α-aminoacid derivatives under anionic and thermal conditions.
