51098-47-6

Upstream product

• 103897-58-1 5-Chloro-2-methyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-pentanoic acid methyl ester 
• 108645-62-1 N-benzyloxycarbonylproline methyl ester 
• 63427-91-8 1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid 
• 141870-95-3 (+/-)-1-benzyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate 

Relevant academic research and scientific papers

Substituted benzoxazoles

The invention relates to substituted benzoxazoles of formula (1) where R1 stands for a group of formula, and a method for preparing same and their use in the production of drugs for the treatment and/or prevention of diseases, in particular cardiovascular diseases, preferably thrombotic or thromboembolic diseases.

SATURATED FUSED [1,2-B] PYRIDAZINONE COMPOUNDS

The invention is directed to saturated fused [1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

REACTION OF SCHIFF BASES ANIONS WITH α,ω-DIHALOALKENES : SYNTHETIC ROUTE TO CYCLIC α-AMINOACID DERIVATIVES.

Imine anions of α-aminoesters, obtained from LDA/THF, undergo copper-catalyzed substitution reactions with α,ω-dihaloalkanes to lead to ω-haloalkylimines which are converted to cyclic α-aminoacid derivatives under anionic and thermal conditions.