1038992-67-4Relevant academic research and scientific papers
Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. Separation of the antithrombotic effect and bleeding for candidate drug AZD1283
Bach, Peter,Antonsson, Thomas,Bylund, Ruth,Bj?rkman, Jan-Arne,?sterlund, Krister,Giordanetto, Fabrizio,Van Giezen,Andersen, S?ren M.,Zachrisson, Helen,Zetterberg, Fredrik
, p. 7015 - 7024 (2013)
Synthesis and structure-activity relationships of ethyl 6-aminonicotinate acyl sulfonamides, which are potent antagonists of the P2Y12 receptor, are presented. Shifting from 5-chlorothienyl to benzyl sulfonamides significantly increased the pot
New Pyridine Analogues VII 543
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Page/Page column 23, (2008/12/07)
The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases
