103910-14-1

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 5-(benzoylamino)-1,6-dihydro-2-methyl-6-oxo-, ethyl ester
• CAS NO: 103910-14-1
• Molecular Formula: C16H16N2O4
• Molecular Weight: 300.314
• Mol File: 103910-14-1.mol

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 5-(benzoylamino)-1,6-dihydro-2-methyl-6-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 5-(benzoylamino)-1,6-dihydro-2-methyl-6-oxo-, ethyl ester(103910-14-1)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 5-(benzoylamino)-1,6-dihydro-2-methyl-6-oxo-, ethyl ester(103910-14-1)

Safety Data

• Hazardous Substances Data: 103910-14-1(Hazardous Substances Data)

Upstream product

• 626-34-6 ethyl 3-aminobut-2-enoate 
• 15646-46-5 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one 
• 103910-15-2 3-benzamido-4-ethoxy-5-ethoxycarbonyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyridine 
• 626-34-6 ethyl aminocrotonate 

Relevant articles and documents

Microwave-mediated domino reactions in dry medium. Preparation of dihydropyridinones and pyridinones structurally related to Hantzsch esters

Microwave irradiation of mixtures of 4-arylmethylene-2-phenyloxazol-5(4H)-ones and enaminocarbonyl compounds, in the absence of solvent, affords dihydropyridinone derivatives in quantitative yields. From 4-ethoxymethylene-2-phenyloxazol-5(4H)one and enami

Studies on Amino Acid Derivatives. IV. Synthesis of 3-Amino-2(1H)-pyridone Derivatives Using 4-Ethoxymethylene-2-phenyl-5-oxazolone

The reaction of 4-ethoxymethylene-2-phenyl-5-oxazolone (1) with 3-amino-2-butanoates (2a-2c) gave 1-substituted 3-benzamido-5-ethoxycarbonyl-6-methyl-2-(1H)-pyridones (4a-4c) in 56-77percent yields.Similarly, compound 1 reacted with 3-amino-2-butenamides (3a and 3b) to yield 1-substituted 3-benzamido-5-carbamoyl-6-methyl-2(1H)-pyridones (7a and 7b).In the reaction of compound 1 with arylaminobutenamides (3c and 3d), 5-carbamoyl-2(1H)-pyridones (7c and 7d) and 5-cyano-2(1H)-pyridones (8c and 8d) were obtained.Keywords---hippuric acid; 3-benzamido-2-pyridone derivative; 4-ethoxymethylene-2-phenyl-5-oxazolone; 3-amino-2-butenoate; 3-amino-2-butenamide; ring transformation

ETUDE DE LA REACTIVITE D'YLIDENEOXAZOLINE-5-ONES VIS-A-VIS DE COMPOSES ENAMINOCARBONYLES.

Reactions between 4-ylideneoxazolin-5-ones and enaminocarbonyl compounds do not lead to 4,7-dihydrooxazolopyridines.These reactions yield, by cleavage of the five-membered ring, monocyclic derivatives whose structures are elucidated.Thus, starting from 4-arylideneoxazolin-5-ones, mixtures of cis and trans dihydro-α-pyridones are formed but, in most cases, only the cis isomers can be isolated.Starting from 2-phenyl-4-ethoxymethyleneoxazolin-5-one, reactions proceed, in addition, by loss of ethanol and α-pyridones are obtained.