10394-96-4Relevant academic research and scientific papers
Oxidative Olefination of Benzylamine with an Active Methylene Compound Mediated by Hypervalent Iodine (III)
Rupanawar, Bapurao D.,Veetil, Sruthi M.,Suryavanshi, Gurunath
, p. 6232 - 6239 (2019)
Hypervalent iodine-mediated oxidative olefination of amines with an active methylene compound provides a rapid gateway towards the formation of electrophilic alkenes under mild reaction conditions in good to excellent yields. This is an efficient protocol for the preparation of substituted electrophilic alkenes.
Green synthesis of a nano salt and its application as multifunctional organocatalyst for Knoevenagel condensation
Honarmand, Moones
, p. 6421 - 6432 (2017)
1,2-Ethanediammonium 3-hydroxypropane-1-sulfonate [(EDA)(HPS)] as a novel nano multifunctional organosalt was synthesized via a simple and green chemical route and characterized using various techniques such as proton nuclear magnetic resonance (1/s
Zirconium-mediated multicomponent reactions of 1,3-butadiynes with ylidenemalononitriles to form functionalized 1,8-naphthyridine and cyclopenta[b]pyridine derivatives
Yu, Shasha,Sun, Renhong,Chen, Haoyi,Xie, Xin,Liu, Yuanhong
, p. 1420 - 1424 (2015)
Zirconocene-mediated multicomponent reactions of 1,3-butadiynes with ylidenemalononitriles in the absence or presence of CuCl have been developed. In the absence of CuCl, 1,3-butadiyne couples with three molecules of ylidenemalononitriles to yield azazirconacycles bearing a hexahydro-1,8-naphthyridine skeleton with high stereoselectivity. In the presence of CuCl, cyclopenta[b]-pyridine or cyclopenta[ b ]quinolin-1-one derivatives are obtained via transmetalation of Zr-C bond to Cu-C bond as the key reaction step. These domino-type reactions proceed with high chemo-, regio- and/or stereoselectivities, and allowing the formation of multiple C-N and C-C bonds in a single operation.
Silica gel catalysed Knoevenagel condensation in dry media under microwave irradiation
De La Cruz, Pilar,Diez-Barra, Enrique,Loupy, Andre,Langa, Fernando
, p. 1113 - 1116 (1996)
Neutral silica gel catalysed efficiently the Knoevenagel condensation of carbonyl compounds on malononitrile in dry media under microwave irradiation. Synergy between dry media and microwaves is shown.
Montmorillonite K-10 catalyzed Knoevenagel condensation under microwave irradiation in solventless system
Heravi, Majid M.,Tajbakhsh, Mahmood,Mohajerani, Bagher,Ghassemzadeh, Mitra
, p. 541 - 543 (1999)
Montmorillonite K-10 catalyzed efficiently the Knoevenagel condensation of carbonyl compounds with malonitrile and ethylcyanoacetate in dry media under microwave irradiation.
The Knoevenagel condensation using quinine as an organocatalyst under solvent-free conditions
Jain, Kavita,Chaudhuri, Saikat,Pal, Kuntal,Das, Kalpataru
supporting information, p. 1299 - 1304 (2019/01/21)
The Knoevenagel condensation between active methylene compounds and aromatic carobonyl compounds has been developed using quinine as an organocatalyst to afford various electrophilic alkenes in excellent yields (up to 90%). In the presence of a catalytic amount of quinine (15 mol%), the reaction proceeded at room temperature (RT) under solvent-free conditions. In this green approach, the organocatalyst was recovered and recycled for up to four cycles without appreciable loss of activity.
Sterically congested ester formation from α-substituted malononitrile and alcohol by an oxidative method using molecular oxygen
Hayashi, Yujiro,Li, Jing,Asano, Hirotaka,Sakamoto, Daisuke
supporting information, p. 675 - 677 (2018/11/23)
A metal-free oxidative esterification or thio-esterifica-tion of readily available substituted malononitrile and alcohol or thiol has been developed by simply mixing α-substituted malononitrile and alcohol or thiol in the presence of base under a molecular oxygen atmosphere. Sterically hindered ester or thioester can be prepared efficiently.
Synthesis of 2-cyanoacrylamides through Pd-catalyzed monohydration of methylenemalononitriles
Liu, Yingtian,Dang, Xinxin,He, Yu,Bai, Hudong,Chen, Xuehong,Li, Jun-Long,Fan, Junting,Jiang, Hezhong,Li, Jiahong
, p. 662 - 671 (2019/02/20)
A straightforward and efficient method has been developed for the synthesis of 2-cyanoacrylamide from 2-methylenemalononitriles through monohydration. A series of methylenemalononitriles underwent the reaction under mild and simple reaction conditions wit
Knoevenagel Condensation of Aldehydes and Ketones with Malononitrile Catalyzed by Amine Compounds-Tethered Fe3O4@SiO2 Nanoparticles
de Resende Filho, Jo?o Batista M.,Pires, Gilvan P.,de Oliveira Ferreira, Jo?o Marcos Gomes,Teotonio, Ercules E. S.,Vale, Juliana A.
, p. 167 - 180 (2017/02/10)
Abstract: A new magnetic nanoparticle supported-catalyst was developed for the Knoevenagel condensation between malononitrile and several aldehydes. The Fe3O4@SiO2-3N (where 3N = N1-(3-trimethoxysilylpropyl)diet
Dual functionalization of porous aromatic frameworks as a new platform for heterogeneous cascade catalysis
Zhang, Yiming,Li, Baiyan,Ma, Shengqian
supporting information, p. 8507 - 8510 (2014/07/22)
Dual functionalization of porous aromatic frameworks (PAFs) has been illustrated in the context of incorporating two antagonistic sites of strong acid and strong base into the highly porous and highly robust PAF-1 via stepwise post-synthetic modification. The resulting bifunctionalized PAF-1 exhibits excellent performances in catalyzing a series of cascade reactions and demonstrates superior chemical stability compared to the counterparts of mesoporous silica and MOFs, thereby opening the door for dual functionalization of PAFs as a new platform for heterogeneous cascade catalysis. the Partner Organisations 2014.
