103959-91-7

Basic information

• Product Name: (S)-2-(benzyloxy)-2-{(S)-1',4'-dioxaspiro[4.5]decan-2'-yl}ethan-1-ol
• Synonyms: (S)-2-(benzyloxy)-2-{(S)-1',4'-dioxaspiro[4.5]decan-2'-yl}ethan-1-ol
• CAS NO: 103959-91-7
• Molecular Weight: 292.375
• Mol File: 103959-91-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-(benzyloxy)-2-{(S)-1',4'-dioxaspiro[4.5]decan-2'-yl}ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(benzyloxy)-2-{(S)-1',4'-dioxaspiro[4.5]decan-2'-yl}ethan-1-ol(103959-91-7)
• EPA Substance Registry System: (S)-2-(benzyloxy)-2-{(S)-1',4'-dioxaspiro[4.5]decan-2'-yl}ethan-1-ol(103959-91-7)

Safety Data

• Hazardous Substances Data: 103959-91-7(Hazardous Substances Data)

Upstream product

• 933-40-4 cycloxexanone dimethyl ketal 
• 84379-51-1 2-O-benzyl-L-threitol 
• 108-94-1 cyclohexanone 
• 100-52-7 benzaldehyde 
• 38270-72-3 dimethyl 2,3-O-benzylidene-L-tartrate 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 78008-36-3 (S)-cyclohexylidene glyceraldehyde 
• 103960-01-6 Benzoic acid (R)-(S)-1-(1,4-dioxa-spiro[4.5]dec-2-yl)-ethyl ester 
• 103959-93-9 (S)-2-((S)-1-Benzyloxy-ethyl)-1,4-dioxa-spiro[4.5]decane 
• 103959-92-8 Toluene-4-sulfonic acid (S)-2-benzyloxy-2-(S)-1,4-dioxa-spiro[4.5]dec-2-yl-ethyl ester 

Relevant articles and documents

Molecular Design toward Biologically Significant Compounds Based on Platelet Activating Factor: A Highly Selective Agonist as a Potential Antihypertensive Agent

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Synthesis and anticancer profile of novel sphingoid base-like compounds with a quaternary stereocentre

The synthesis of novel sphingoid base-like compounds with a quaternary stereocentre was achieved in a sequence featuring [3,3]-sigmatropic rearrangements and olefin cross-metathesis transformation as the key reaction steps, which were accompanied by the rational selection of suitable functional group transformations. The stereochemistry of the desired tetra-substituted carbon bearing nitrogen functionality was determined via NOESY experiments of the advanced oxazolidine-2-thiones. Cell viability experiments revealed significant antiproliferative/cytotoxic activity of the target compounds 7, ent-7 and 29 against the Jurkat cell line, with the IC50 values of 6.6 μM, 5.6 μM and 6.1 μM, respectively.