103963-35-5Relevant articles and documents
Palladium Catalysed Cross-Coupling of Vinyl Triflates with 9-Alkyl-9-borobicyclononanes. Total Synthesis of (-)-Isoseiridine.
Grigg, Ronald,Kennewell, Peter,Savic, Vladimir
, p. 5489 - 5494 (2007/10/02)
Pd(O) Catalysed cross-coupling of butenolide-3-triflates to 9-alkyl-9-borobicyclononanes occurs in moderate to good yield and tolerates a range of functionality.Application of this methodology combined with addition of diethylzinc to a butenolide aldehyde in the presence of an ephedrine derivative leads to a 3-step synthesis of (-)-isoseiridine with 88percent e.e. in good yield.