10399-81-2Relevant articles and documents
First synthesis of indirubin N-glycosides (red sugars)
Libnow, Stefanie,Hein, Martin,Michalik, Dirk,Langer, Peter
, p. 6907 - 6909 (2006)
The first indirubin N-glycosides were prepared by reaction of isatine N-glycosides with indoxyl acetate under basic conditions.
Synthesis and bioactivity of N-glycosylated 3-(2-oxo-2-arylethylidene)-indolin-2-ones
Kleeblatt, Dennis,Becker, Martin,Pl?tz, Michael,Sch?nherr, Madeleine,Villinger, Alexander,Hein, Martin,Eberle, Jürgen,Kunz, Manfred,Rahman, Qamar,Langer, Peter
, p. 20769 - 20782 (2015)
N-Glycosyl-3-alkylideneoxindoles, N-glycosylated 3-(2-oxo-2-arylethylidene)indolin-2-ones, were prepared by reaction of isatin-N-glycosides with substituted acetophenones. The biological activities of these new compounds revealed significant antitumor act
Synthesis and antiproliferative activity of N-glycosyl-3,3-diaryloxindoles
Kleeblatt, Dennis,Cordes, Christoph A.,Lebrenz, Philipp,Hein, Martin,Feist, Holger,Matin, Abdul,Raza, Rabia,Iqbal, Jamshed,Munshi, Omar,Rahman, Qamar,Villinger, Alexander,Langer, Peter
, p. 22828 - 22839 (2014/06/24)
N-Glycosylated 3,3-diaryloxindoles were prepared by Lewis acid catalyzed reaction of acetylated N-glycosylisatins with various benzene derivatives and subsequent deprotection. Some of the products showed antiproliferative activity against malignant cutane
Synthesis of thia-analogous indirubin n-glycosides and their influence onmelanoma cell growth and apoptosis
Kunz, Manfred,Driller, Katrin M.,Hein, Martin,Libnow, Stephanie,Hohensee, Ina,Ramer, Robert,Hinz, Burkhard,Berger, Anja,Eberle, Juergen,Langer, Peter
scheme or table, p. 534 - 539 (2010/12/25)
Stopping cancer in its tracks Thia-analogues of indirubin-N-glycosides, prepared by condensation of N-glycosylisatines with thiaindane-3-one and subsequent deprotection, were tested for their activity against malignant melanoma cells. These indirubin-N-gl
