42891-47-4Relevant academic research and scientific papers
Arynes in the Monoarylation of Unprotected Carbohydrate Amines
Pal, Kumar Bhaskar,Mahanti, Mukul,Nilsson, Ulf J.
supporting information, p. 616 - 619 (2018/02/09)
A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderate to good yields with broad scope.
Synthesis and bioactivity of N-glycosylated 3-(2-oxo-2-arylethylidene)-indolin-2-ones
Kleeblatt, Dennis,Becker, Martin,Pl?tz, Michael,Sch?nherr, Madeleine,Villinger, Alexander,Hein, Martin,Eberle, Jürgen,Kunz, Manfred,Rahman, Qamar,Langer, Peter
, p. 20769 - 20782 (2015/03/30)
N-Glycosyl-3-alkylideneoxindoles, N-glycosylated 3-(2-oxo-2-arylethylidene)indolin-2-ones, were prepared by reaction of isatin-N-glycosides with substituted acetophenones. The biological activities of these new compounds revealed significant antitumor act
Stereoselective copper-catalyzed Chan-Lam-Evans N-arylation of glucosamines with arylboronic acids at room temperature
Bruneau, Alexandre,Brion, Jean-Daniel,Alami, Mouad,Messaoudi, Samir
supporting information, p. 8359 - 8361 (2013/09/23)
An efficient and practical N-arylation of glycosylamines with substituted aryl boronic acids has been established. Using Cu(OAc)2 and pyridine at room temperature under air atmosphere, the protocol proved to be general, and a variety of aryl N-glycosides have been prepared in good to excellent yields with exclusive β selectivity.
