10401-12-4

Upstream product

• 42861-71-2 3-iodophenylacetate 
• 626-02-8 3-Iodophenol 
• 164660-78-0 3-(trimethylsilanylethynyl)-phenyl acetate 
• 10401-11-3 3-hydroxy phenylacetylene 
• 108-24-7 acetic anhydride 

Downstream Products

• 1205560-25-3 N-benzyl-2-[2-(3-hydroxyphenyl)-ethyn-1-yl]-4-methyl-1,3-thiazole-5-carboxamide 
• 1190880-84-2 C₃₆H₃₉NO₄S₂ 
• 1190883-60-3 C₃₂H₃₇NO₄S 
• 1029359-08-7 3-({6-[4-(cyclohexylmethyl)piperazin-1-yl]pyridazin-3-yl}ethynyl)phenyl acetate 
• 1029361-20-3 3-({6-[4-(cyclopropylmethyl)piperazin-1-yl]pyridazin-3-yl}ethynyl)phenyl acetate 

Relevant academic research and scientific papers

Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids

Naphthalene diimides with one or two centrosymmetric arylethynyl moieties capable of synergic donor and acceptor hydrogen bonding exhibit promising binding properties and selectivity towards parallel G-quadruplex (G4) nucleic acids (c-myc, bcl-2 and parallel hTel22). The hydrogen-bonding network involving the phosphate backbone and outside rim of the G-quartet represents an opportunity to exploit G4 selectivity for extended aromatics.

THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS

The present invention provides thiazole derivatives as Stearoyl CoA Desaturase (SCD) inhibitors. In particular, the compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by Stearoyl CoA Desaturase

Polymer-supported gadolinium triflate as a convenient and efficient Lewis acid catalyst for acetylation of alcohols and phenols

A polymer-supported gadolinium triflate (CMPS-IM-Gd) catalyst was prepared from chloromethyl polystyrene (CMPS) resin using a simple and convenient procedure. This polymeric catalyst was used as an efficient Lewis acid catalyst for the acetylation of various alcohols and phenols with acetic anhydride, affording high yields under mild conditions. The reaction was completed in a short period of time with small amounts of the catalyst. The catalyst was reused over 10 times without any significant loss of its catalytic activity.