1040124-26-2Relevant articles and documents
The concise synthesis of a key intermediate for the total synthesis of fumagillin, TNP-470, and ovalicin
Yadav, Jhillu S.,Sreedhar, Pamu,Srihari, Pabbaraja,Sarma, Ganti Dattatreya,Jagadeesh, Bharatam
, p. 1460 - 1466 (2008)
The facile synthesis of a key intermediate for the total synthesis of the antiangiogenic compound fumagillin, its semisynthetic analogue TNP-470, and ovalicin is described. The methodology employs a Diels-Alder strategy and a zinc-mediated ring-opening reaction to realize the cyclohexane backbone. Georg Thieme Verlag Stuttgart.