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10402-33-2

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10402-33-2 Usage

Description

Eugenyl Phenylacetate is a chemical compound known for its floral scent, derived from eugenol found in essential oils such as nutmeg, clove, cinnamon, and bay leaf. It features both phenyl and acetate components, which contribute to its aromatic properties. EUGENYL PHENYLACETATE's chemical properties enable it to deliver a strong and long-lasting scent, making it a popular choice in the perfume industry. However, its potential toxicity or environmental effects are not well-documented, so caution is advised in its use.

Uses

Used in Perfumery Industry:
Eugenyl Phenylacetate is used as a fragrance ingredient for its floral scent and strong, long-lasting aroma. It is incorporated into perfumes and other fragranced products to enhance their scent profiles and provide a pleasant olfactory experience.
Used in Flavor Industry:
Although not explicitly mentioned in the provided materials, eugenyl phenylacetate, due to its aromatic properties, could potentially be used in the flavor industry to add depth and complexity to food and beverage products, particularly those with floral or spicy notes.

Check Digit Verification of cas no

The CAS Registry Mumber 10402-33-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,0 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10402-33:
(7*1)+(6*0)+(5*4)+(4*0)+(3*2)+(2*3)+(1*3)=42
42 % 10 = 2
So 10402-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H18O3/c1-3-7-14-10-11-16(17(12-14)20-2)21-18(19)13-15-8-5-4-6-9-15/h3-6,8-12H,1,7,13H2,2H3

10402-33-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-methoxy-4-prop-2-enylphenyl) 2-phenylacetate

1.2 Other means of identification

Product number -
Other names ACETIC ACID,PHENYL-,4-ALLYL-2-METHOXYPHENYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10402-33-2 SDS

10402-33-2Downstream Products

10402-33-2Relevant articles and documents

Eugenol derived immunomodulatory molecules against visceral leishmaniasis

Charan Raja, Mamilla R.,Velappan, Anand Babu,Chellappan, Davidraj,Debnath, Joy,Kar Mahapatra, Santanu

, p. 503 - 518 (2017/08/22)

Visceral leishmaniasis (VL) is a life threatening infectious disease caused by Leishmania donovani. It leads to the severe immune suppression in the host defense system. Higher cytotoxicity, rigorous side effects and lower therapeutic indexes (TI) of current antileishmanial drugs have created a necessity to develop new molecules with better antileishmanial activity and high TI value. In this study, we have synthesized 36 derivatives of eugenol and screened them for their activity against promastigote and amastigote forms of L. donovani. Among the synthesized derivatives, comp.35 showed better antileishmanial activity against extra cellular promastigotes (IC50- 20.13 ± 0.91 μM) and intracellular amastigotes (EC50-4.25 ± 0.26 μM). The TI value (82.24 ± 3.77) was found to improve by 10–13 fold compared to Amphotericin B and Miltefosine respectively. Treatment with comp.35 (5 μg/ml) enhanced the nitric oxide (NO) generation, iNOS2 mRNA expression (~8 folds increase) and decreased the arginase-1 activity (~4 folds) in L. donovani infected peritoneal macrophages. Comp.35 had also increased the IL-12 (~6 folds) and decreased the IL-10 (~3 folds) mRNA expression and release in vitro. Results of in vivo studies revealed that comp.35 treatment at 25 mg/kg body weight efficiently cleared the hepatic and splenic parasite burden with enhanced Th1 response in L. donovani infected BALB/c mice. Hence, this study clearly represents comp.35, as an immunomodulatory molecule, can induce host protective immune response against visceral leishmaniasis through enhanced NO generation and Th1 response, which are essentials against this deadly disease.

Eugenol derivatives as potential anti-oxidants: Is phenolic hydroxyl necessary to obtain an effect?

D'Avila Farias, Marilia,Oliveira, Pathise Souto,Dutra, Filipe S. Pereira,Fernandes, Thiely Jacobsen,De Pereira, Claudio M. P.,De Oliveira, Simone Quintana,Stefanello, Francieli Moro,Lencina, Claiton Leonetti,Barschak, Alethea Gatto

, p. 733 - 746 (2014/05/06)

Objectives Eugenol, obtained from clove oil (Eugenia caryophyllata), possess several biological activities. It is anti-inflammatory, analgesic, anaesthesic, antipyretic, antiplatelet, anti-anaphylactic, anticonvulsant, anti-oxidant, antibacterial, antidepressant, antifungal and antiviral. The anti-oxidant activity of eugenol have already been proven. From this perspective testing, a series of planned structural derivatives of eugenol were screened to perform structural optimization and consequent increase of the potency of these biological activities. Methods In an attempt to increase structural variability, 16 compounds were synthesized by acylation and alkylation of the phenolic hydroxyl group. Anti-oxidant activity capacity was based on the capture of DPPH radical (2,2-diphenyl-1-picryl-hydrazyl), ABTS radical 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid), measure of TBARS (thiobarbituric acid-reactive species), total sulfhydryl and carbonyl content (eugenol derivatives final concentrations range from 50 to 200 μm). Key findings Four derivatives presented an efficient concentration to decrease 50% of the DPPH radical (EC50) 100 μm, which has a good potential as a free-radical scavenger. Three of these compounds also showed reduction of ABTS radical. Eugenol derivatives presenting alkyl or aryl (alkylic or arylic) groups substituting hydroxyl 1 of eugenol were effective in reducing lipid peroxidation, protein oxidative damage by carbonyl formation and increase total thiol content in cerebral cortex homogenates. In liver, the eugenol derivatives evaluated had no effect. Conclusions Our results suggest that these molecules are promising anti-oxidants agents.

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