1040741-72-7Relevant academic research and scientific papers
New MCR-Heck-isomerization cascade toward indoles
El Kaim, Laurent,Gizzi, Marion,Grimaud, Laurence
supporting information; experimental part, p. 3417 - 3419 (2009/05/07)
(Chemical Equation Presented) The use of ortho-iodonitrophenol in Ugi-Smiles reaction coupled with Heck cyclization gives new access to indole scaffolds. The sequence can be performed in a one-pot reaction if the residual isocyanide is neutralized prior to the addition of the palladium catalyst.
