104075-51-6

Basic information

• Product Name: Benzenepropanoic acid, a-acetyl-2-methyl-, ethyl ester
• CAS NO: 104075-51-6
• Molecular Formula: C14H18O3
• Molecular Weight: 234.295
• Mol File: 104075-51-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-acetyl-2-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-acetyl-2-methyl-, ethyl ester(104075-51-6)
• EPA Substance Registry System: Benzenepropanoic acid, a-acetyl-2-methyl-, ethyl ester(104075-51-6)

Safety Data

• Hazardous Substances Data: 104075-51-6(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 552-45-4 1-chloromethyl-2-methylbenzene 
• 89-92-9 2-methylbenzyl bromide 

Downstream Products

• 1091602-23-1 C₁₈H₂₁N₃O₄S 
• 1263575-78-5 5-methyl-4-(2-methylbenzyl)-2-phenyl-3,4-dihydro-2H-pyrazol-3-one 
• 161461-12-7 ethyl 2-chloro-2-(o-methylbenzyl)-acetoacetate 
• 127459-68-1 7-(2-methylphenyl)-2,5-dimethylhept-3-yne-2,5-diol 
• 127459-69-2 7-(2-methylphenyl)-2,5-dimethylheptane-2,5-diol 
• 57132-25-9 4-(2-methylphenyl)butan-2-one 

Relevant articles and documents

Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

We optimized the structure of an active metabolite (1) of WAY-123783, which was obtained from mouse urine after oral administration, to improve selectivity for SGLT2 and oral bioavailability. O-glucoside derivative 24 (remogliflozin etabonate) was subsequently identified as a potent, highly selective, and orally available SGLT2 inhibitor.

Carbonic anhydrase inhibitors: Synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides

A series of 2-(hydrazinocarbonyl)-3-substitutedphenyl-1H-indole-5-sulfonamides possessing various 2-, 3- or 4- substituted phenyl groups with methyl-, halogeno- and methoxy- functionalities, as well as the perfluorophenyl moiety have been synthesized and

Phenylethl o-methylcinnamate, a process for preparation and a fragrance composition containing same

The invention relates to phenylethyl o-methylcinnamate and a process for its preparation. Phenylethyl o-methylcinnamate is prepared by, first, alkylating ethyl acetoacetate with o-methylbenzyl chloride in the presence of a phase transfer catalyst to yield 2-(o-methylbenzyl)-acetoacetate. Thereafter the 2-(o-methylbenzyl)-acetoacetate yielded in the alkylating step is halogenated to yield ethyl 2-halo-2-(o-methylbenzyl)-acetoacetate. This is followed by degarding the ethyl 2-halo-2-(o-methylbenzyl)-acetoacetate acid. Finally the o-methylcinnamic acid obtained in the degarding step is esterified with 2-phenylethanol into phenylethyl o-methylcinnamate. A fragrance composition utilizing phenylethyl o-methylcinnamate is also disclosed.