104085-54-3Relevant academic research and scientific papers
Diastereoselective Aldol Reactions of β-Silylenolates
Fleming, Ian,Kilburn, Jeremy D.
, p. 305 - 306 (1986)
β-Silylenolates react with aldehydes with high diastereoselectivity with respect to both new chiral centres, the relative stereochemistry in the aldol relationship being dependent upon the geometry of the enolate double bond.
Diastereocontrol in open-chain nucleophilic attack on a double bond adjacent to a stereogenic centre carrying a silyl group
Betson, Mark S.,Fleming, Ian,Ouzman, Jacqueline V.A.
, p. 4017 - 4024 (2007/10/03)
The bis[dimethyl(phenyl)silyl]cuprate reagent introduces a silyl group to the β-position of three α,β-unsaturated esters: methyl Z-4-dimethyl(phenyl)silylpent-2-enoate 11, and methyl Z- and E-(1′-dimethylphenylsilylbenzyl)but-2-enoates 14 and 15, diastere
The Diastereoselectivity of Electrophilic Attack on Trigonal Carbon Adjacent to a Stereogenic Centre: Diastereoselective Aldol Reactions of Open-chain Enolates having a Stereogenic Centre carrying a Silyl Group at the β Position
Fleming, Ian,Kilburn, Jeremy D.
, p. 3295 - 3302 (2007/10/02)
Trigonal electrophiles react with lithium enolates having β-silyl groups 2, or with the corresponding silyl enol ethers 7, with high diastereoselectivity in the sense 1, to give largely the anti products 3.Aldehydes react with the same lithium enolates 2,
