104086-21-7

Basic information

• Product Name: ethyl 6-(aminomethyl)picolinate
• Synonyms: ethyl 6-(aminomethyl)picolinate;Ethyl 6-(aminomethyl)pyridine-2-carboxylate;2-Pyridinecarboxylic acid, 6-(aMinoMethyl)-, ethyl ester;6-(AMinoMethyl)-2-pyridinecarboxylic acid ethyl ester;ethyl 6-(aminomethyl)picolite
• CAS NO: 104086-21-7
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.206
• Mol File: 104086-21-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 319.7 °C at 760 mmHg
• Flash Point: 147.2 °C
• Appearance: /
• Density: 1.147 g/cm³
• Vapor Pressure: 0.000333mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.44±0.39(Predicted)
• CAS DataBase Reference: ethyl 6-(aminomethyl)picolinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-(aminomethyl)picolinate(104086-21-7)
• EPA Substance Registry System: ethyl 6-(aminomethyl)picolinate(104086-21-7)

Safety Data

• Hazardous Substances Data: 104086-21-7(Hazardous Substances Data)

Usage

Description

Ethyl 6-(aminomethyl)picolinate, with the molecular formula C10H14N2O2, is an ester derivative of picolinic acid. It is recognized for its role as a building block in the synthesis of pharmaceuticals and organic compounds. ethyl 6-(aminomethyl)picolinate is also known for its chelating properties, which are valuable in the preparation of coordination complexes for chemical research. Its unique chemical properties and structural characteristics suggest potential applications in drug development and material science.

Uses

Used in Pharmaceutical Synthesis:
Ethyl 6-(aminomethyl)picolinate is used as a building block for the synthesis of various pharmaceuticals and organic compounds, contributing to the development of new medicines and chemical entities.
Used in Chemical Research:
As a chelating agent, ethyl 6-(aminomethyl)picolinate is used in the preparation of coordination complexes, which is crucial for advancing chemical research and understanding the interactions between metal ions and organic ligands.
Used in Drug Development:
Due to its unique chemical properties, ethyl 6-(aminomethyl)picolinate may have potential applications in the development of new drugs, potentially leading to innovative therapeutic agents.
Used in Material Science:
The structural characteristics of ethyl 6-(aminomethyl)picolinate suggest its potential use in the development of new materials, possibly contributing to advancements in various industries that rely on novel materials with specific properties.

InChI:InChI=1/C9H12N2O2/c1-2-13-9(12)8-5-3-4-7(6-10)11-8/h3-5H,2,6,10H2,1H3

Upstream product

• 1258831-91-2 ethyl 6-{[bis(tert-butoxycarbonyl)amino]methyl}pyridine-2-carboxylate 
• 49668-99-7 ethyl 6-chloromethylpyridine-2-carboxylate 
• 41337-81-9 ethyl 6-(hydroxymethyl)pyridine-2-carboxylate 
• 15658-60-3 diethyl-2,6-pyridinedicarbonyl ester 
• 944150-30-5 ethyl 6-((1,3-dioxoisoindolin-2-yl)methyl)picolinate 

Downstream Products

• 885276-19-7 imidazo[1,5-a]pyridine-5-carboxylic acid 
• 85691-71-0 5-formylimidazo<1,5-a>pyridine 
• 76292-67-6 ethyl imidazo [1,5-a]pyridine-5-carboxylate 
• 1350754-04-9 3-(benzyloxycarbonylamino)imidazo[1,5-a]pyridine-5-carboxylic acid ethyl ester 
• 1258832-20-0 6-{[3-(3-(benzylamino)-3-oxopropyl)-2-((benzyloxy)carbonyl)guanidino]methyl}picolinic acid ethyl ester 
• 1350753-98-8 6-(3-[benzyloxycarbonyl]-2-thioureidomethyl)pyridine-2-carboxylic acid ethyl ester 

Relevant articles and documents

Relationship between the ligand structure and the luminescent properties of water-soluble lanthanide complexes containing bis(bipyridine) anionic arms

A series of six new ligands (L1-L6) suitable for the formation of luminescent lanthanide complexes in water is described. Ligands L1-L4 are constructed from two 6′-carboxy-6- methylene-2,2′-bipyridine chromophoric arms bonded to the amino function of a 2-aminomethylene-6-carboxy-pyridine (L1), an N,N-diacetate-ethylene diamine (L2), a serine (L3), or an aminomalonic acid (L4). For ligands L5 and L6, the linking amino function is provided by a glutamic acid, and the anionic functions at the 6′-position of the bipyridyl arms are made of the sodium salts of monoethylphosphonic ester (L5) and phosphonic acid (L6). The synthesis and characterisation of the ligands are described, together with the study of the formation of lanthanide complexes with europium and terbium. In the case of L3, the europium complex obtained in acidic conditions was crystallised and the X-ray crystal structure is depicted. Photophysical properties of the complexes were studied by means of UV-visible absorption, and steady-state and time-resolved luminescence spectroscopy. Excited-state luminescence lifetimes of the complexes were determined in water and deuterated water to gain insight into the number of water molecules directly coordinated in the first coordination sphere of the complexes. The coordination behaviour of the series of ligands is questioned in the light of the spectroscopic data and discussed in terms of protection of the cation towards water molecules and their impact on the luminescence efficiency.

Synthesis and binding properties of guanidinium biscarboxylates

The ammonium ion binding site of the enzyme glutaminase HisF inspired us to design guanidinium biscarboxylates as potential self-organized ionophores in molecular recognition. The syntheses of the title compounds based on aliphatic and aromatic building b

Functional Micellar Catalysis. Part 8. Catalysis of the Hydrolysis of p-Nitrophenyl Picolinate by Metal-chelating Micelles containing Copper(II) or Zinc(II)

The kinetic analysis of the esterolysis of p-nitrophenyl picolinate in neutral aqueous solutions of Cu2+ and Zn2+ in the presence of co-micelles made up of cetyltrimethylammonium bromide and either 6-(myristoylamido)methylpyridine-2-