104097-04-3Relevant articles and documents
Photochemical Carbon-Phosphorus Bond Cleavage of Nitro-substituted Benzylphosphonic Acids
Okamoto, Yoshiki,Iwamoto, Narimasa,Takamuku, Setsuo
, p. 1516 - 1517 (1986)
Upon u.v.-irradiation, the C-P bond of p-nitrobenzylphosphonate is more readily cleaved to give a monomeric metaphosphate anion as intermediate than those of o- and m-derivatives.
Tunable photophysical properties of thiophene based chromophores: A conjoined experimental and theoretical investigation
Popczyk, Anna,Cheret, Yohan,Grabarz, Anna,Hanczyc, Piotr,Fita, Piotr,El-Ghayoury, Abdelkrim,Sznitko, Lech,Mysliwiec, Jaroslaw,Sahraoui, Bouchta
, p. 6728 - 6736 (2019)
In this paper we report the synthesis and photophysical properties of six novel thiophene derivatives (ThD) with D-π-A structure. The subject of this work is three nitrophenyls (1) BT-Th-NO2 and three benzonitriles (2) BT-Th-CN, substituted at
Synthesis and nonlinear optical properties of push-pull type stilbene and pyrazoline based chromophores
Szukalski,Parafiniuk,Haupa,Goldeman,Sahraoui,Kajzar,Mysliwiec
, p. 507 - 515 (2017/04/17)
In this work we present the synthesis, spectroscopic and nonlinear optical properties of push-pull type organic dyes based on 1-phenyl-2-pyrazoline or 4-(dimethylamino)phenyl chromophores as a donor part, and bridged by a double bound ortho- or meta-subst
AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF
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Paragraph 0454-0455, (2015/03/16)
The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont
Photoisomerization of Trans Ortho-, Meta-, Para-Nitro Diarylbutadienes: A Case of Regioselectivity
Agnihotri, Harsha,Paramasivam, Mahalingavelar,Palakollu, Veerabhadraiah,Kanvah, Sriram
, p. 1324 - 1331 (2015/11/10)
A series of ortho-, meta- and para-substituted trans-nitro aryl (phenyl and pyridyl) butadienes have been synthesized and characterized. The effect of substitution and positional selectivity on their fluorescence and photoisomerization were systematically investigated. Among all dienes, meta- and para-nitro phenyl-substituted derivatives exhibit remarkable solvatochromic emission shifts due to intramolecular charge transfer. On the other hand, ortho derivatives undergo regioselective isomerization upon photoexcitation in contrast to inefficient isomerization of para and meta nitro-substituted dienes. Single crystal X-ray analysis revealed existence of intramolecular hydrogen bonding between the nitro group and the hydrogen of the proximal double bond. This restricts the rotation of the proximal double bond thereby allowing regioselective isomerization. The observations were also supported by NMR spectroscopic studies.
Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus
Davis, Dexter C.,Mohammad, Haroon,Kyei-Baffour, Kwaku,Younis, Waleed,Creemer, Cassidy Noel,Seleem, Mohamed N.,Dai, Mingji
, p. 384 - 390 (2015/07/20)
Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) have emerged as a global health concern. A new class of compounds featuring an aryl isonitrile moiety has been discovered that exhibits potent inhibitory activity against several clinically-relevant MRSA and VRSA isolates. Structure-activity relationship studies have been conducted to identify the aryl isonitrile group as the key functional group responsible for the observed antibacterial activity. The most potent antibacterial aryl isonitrile analogs (MIC 2 μM) did not show any toxicity against mammalian cells up to a concentration of 64 μM.
STAT3 DIMERIZATION INHIBITORS
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Page/Page column 65; 67, (2014/05/24)
The subject matter disclosed herein relates to compositions and methods of making and using the compositions. In a further aspect, the subject matter disclosed herein relates to inhibitors of STAT3 dimerization. Methods of making these compositions as wel
Development of new N-arylbenzamides as STAT3 dimerization inhibitors
Urlam, Murali K.,Pireddu, Roberta,Ge, Yiyu,Zhang, Xiaolei,Sun, Ying,Lawrence, Harshani R.,Guida, Wayne C.,Sebti, Said M.,Lawrence, Nicholas J.
supporting information, p. 932 - 941 (2013/07/27)
The O-tosylsalicylamide S3I-201 (10) was used as a starting point for design and synthesis of novel STAT-3 dimerization inhibitors with improved drug-like qualities. The phosphonic acid 12d and salicylic acids 13f, 13g with a shorter amide linker lacking
AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF
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Page/Page column 141, (2013/04/10)
The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont
(1,1, 1,3, 3, 3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL) PHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR USE FOR THE TREATMENT OF ATHEROSCLEROSIS
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Page/Page column 75, (2011/05/11)
The present invention relates to (1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl derivatives having the general formula (I) to pharmaceutical compositions comprising the same and to the use of these (1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl
