1041170-81-3

Basic information

• Product Name: C₁₆H₂₀O₂
• Synonyms: C₁₆H₂₀O₂
• CAS NO: 1041170-81-3
• Molecular Weight: 244.334
• Mol File: 1041170-81-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₀O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₀O₂(1041170-81-3)
• EPA Substance Registry System: C₁₆H₂₀O₂(1041170-81-3)

Safety Data

• Hazardous Substances Data: 1041170-81-3(Hazardous Substances Data)

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 123405-87-8 (E)-non-3-en-8-yn-2-one 

Relevant articles and documents

Palladium(0)-catalyzed cis-selective alkylative and arylative cyclization of alkynyl enones with organoboron reagents

A palladium(0)-tricyclohexylphosphine catalyzes cis-selective alkylative and arylative cyclization of alkyne-containing electron-deficient alkenes with organoboron reagents to provide five- or six-membered rings with exo tri- or tetra-substituted alkenes. The opposite stereoselectivity to that for the alkyne-aldehyde cyclization using the same reagents would result from palladacycle-forming oxidative addition of the substrates to the Pd0 catalyst followed by transmetalation with the boron reagents, protonation, and reductive elimination. The functional group compatibility, availability, stability, and non-toxicity of the reagents, and the fact that no additives are needed make the process more practical than the Ni0-catalyzed cyclization with organozinc reagents.