1041187-93-2Relevant academic research and scientific papers
A convenient synthesis of novel series of 4-cyclohexyl-2-substituted [1,2,4]triazolo[1,5-a]quinazolin-5(4H)-ones. Novel isomers of H1 antihistaminic activite agents
Shawali, Ahmad S.,Hassaneen, Hamdi M.,Shurrab, Nabil K.
experimental part, p. 1479 - 1488 (2009/04/11)
A novel series of 2,4-disubstituted-1,2,4-triazolo[ 1,5-a]-quinazolin-5(4H)-ones were prepared by Dimroth rearrangement of their respective isomers namely 1,4-disubstituted[1,2,4]triazolo[4,3-a]-quinazolin-5(4H)-ones. The latter were prepared via new synthetic strategy based on 1,5-elecrocyclization of the respective N-(4-oxo-3-cyclohexylquinazolin-2-yl)nitrilimines.
