1041403-36-4

Basic information

• Product Name: N-[(R)-1-phenylprop-2-ynyl]-2-methoxybenzenamine
• Synonyms: N-[(R)-1-phenylprop-2-ynyl]-2-methoxybenzenamine
• CAS NO: 1041403-36-4
• Molecular Weight: 237.301
• Mol File: 1041403-36-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[(R)-1-phenylprop-2-ynyl]-2-methoxybenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(R)-1-phenylprop-2-ynyl]-2-methoxybenzenamine(1041403-36-4)
• EPA Substance Registry System: N-[(R)-1-phenylprop-2-ynyl]-2-methoxybenzenamine(1041403-36-4)

Safety Data

• Hazardous Substances Data: 1041403-36-4(Hazardous Substances Data)

Upstream product

• 16169-88-3 1-phenylprop-2-ynyl acetate 
• 90-04-0 2-methoxy-phenylamine 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 1041403-34-2 (S)-2-methoxy-N-(phenyl(1-phenyl-1H-1,2,3-triazol-4-yl)methyl)aniline 

Relevant articles and documents

Chiral tridentate P,N,N ligands for highly enantioselective copper-catalyzed propargylic amination with both primary and secondary amines as nucleophiles

Chiral tridentate P,N,N ligands have been demonstrated to be highly efficient for the coppercatalyzed enantioselective propargylic amination of propargylic acetates with both primary and secondary amines as nucleophiles, affording the corresponding propar

Enantioselective copper-catalyzed propargylic amination

(Chemical Equation Presented) A proper copper catalyst with a chiral pyridine-2,6-bisoxazoline (pybox) ligand was used to convert a variety of propargylic acetates with aromatic side chains (R = Ar) into their amine counterparts in high yield and with good selectivity (up to 88% ee). The resulting chiral propargylic amines can be elaborated further into P,N ligands (see scheme; DIPEA = diisopropylethylamine).