104152-68-3Relevant academic research and scientific papers
PYRIDAZINES XXVII. ACYLATION REACTIONS AND PROCEDURES FOR REGIOSELECTIVE ALKYLATION OF (5-AMINO-4-PYRIDAZINYL)-ARYLKETONES
Haider, Norbert,Heinisch, Gottfried
, p. 2651 - 2661 (2007/10/02)
Various amides 2a-d, 3, 4 derived from (5-amino-4-pyridazinyl)arylketones were prepared.Amino ketone 1 was found to be attacked by alkyl halides exclusively at N-2 yielding iminium salts 9a, 9b, whereas reaction of tosylamide 3 with methyl iodide/sodium h
