104155-55-7

Upstream product

• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 1663-67-8 malonoyl dichloride 

Downstream Products

• 108298-55-1 3-Methyl-5-(trimethylsiloxy)phthalsaeure-dimethylester 
• 590410-77-8 4-hydroxy-6-methyl-3-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2-pyrone 
• 590410-78-9 4-hydroxy-6-methyl-3-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-pyrone 
• 934296-28-3 C₃₆H₄₇NO₃Si 
• 880152-35-2 2-[4-(tert-butyl-diphenyl-silanyloxy)-3-(6-butyl-2-oxo-2H-pyran-4-ylamino)-butyl]-cyclohex-1-enecarbaldehyde 
• 934296-47-6 3-(tert-butyl-diphenyl-silanyloxymethyl)-5-hexyl-decahydro-pyrrolo[2,1-j]quinoline 
• 880152-44-3 C₃₆H₄₄ClNO₄Si 
• 880152-33-0 acetic acid 2-[4-(tert-butyl-diphenyl-silanyloxy)-3-(6-butyl-2-oxo-2H-pyran-4-ylamino)-butyl]-cyclohex-1-enylmethyl ester 
• 880152-40-9 C₃₆H₄₇NO₄Si 
• 880152-39-6 C₃₆H₄₅NO₄Si 
• 880152-45-4 C₃₆H₄₇NO₃Si 
• 880152-36-3 C₃₆H₄₅NO₃Si 
• 880152-43-2 C₃₆H₄₅NO₃Si 
• 880152-41-0 3-(tert-butyl-diphenyl-silanyloxymethyl)-5-hexyl-2,3,8,9,10,11-hexahydro-1H,7aH-pyrrolo[2,1-j]quinolin-7-one 

Relevant academic research and scientific papers

Enol Ethers, XVII. Acylation of Trimethylsilyl Enol Ethers with Malonyl Dichloride - Synthesis of 4-Hydroxy-2H-pyran-2-ones

Trimethylsilyl enol ethers of aldehydes 1, acyclic and cyclic ketones 4 and 10, respectively, are acylated by malonyl dichloride (2) at room temperature or even at -60 deg C.After aqueous workup, the 6-unsubstituted 4-hydroxy-2H-pyran-2-ones 3 are obtained from 1-(trimethylsiloxy)alkenes 1, whereas the 5,6-alkylene-bridged 4-hydroxy-2H-pyran-2-ones 11 are formed from 1-(trimethylsiloxy)cycloalkenes 10.Acylation of 2-(trimethylsiloxy)-1-propene (4a) and 3-(trimethylsiloxy)-2-pentene (4b) results in mixtures of 4-(trimethylsiloxy)-2H-pyran-2-ones 5 (main products) and phloroglucinol tris(trimethylsilyl) ethers (6) (by-products).