10417-63-7 Usage
Uses
Used in Pharmaceutical Industry:
11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione is used as an anti-inflammatory agent for the treatment of various inflammatory conditions, such as rheumatoid arthritis, systemic lupus erythematosus, and asthma. Its potent anti-inflammatory action helps to reduce inflammation, swelling, and pain associated with these conditions.
Used in Medical Treatments:
In the medical field, 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione is used as an immunosuppressive agent to prevent organ transplant rejection and to treat autoimmune diseases. Its ability to suppress the immune system makes it a valuable tool in managing conditions where the immune system is overactive or attacking healthy tissues.
Used in Dermatology:
11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione is also used in dermatology for the treatment of various skin conditions, such as eczema, psoriasis, and allergic reactions. Its anti-inflammatory and immunosuppressive properties help to reduce skin inflammation and itching, providing relief to patients suffering from these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 10417-63-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,1 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10417-63:
(7*1)+(6*0)+(5*4)+(4*1)+(3*7)+(2*6)+(1*3)=67
67 % 10 = 7
So 10417-63-7 is a valid CAS Registry Number.
10417-63-7Relevant academic research and scientific papers
Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
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, (2008/06/13)
This invention discloses an improved process for the production of corticoids from 17α-hydroxy steroids utilizing peroxymonosulfate.
Cytotoxic nucleoside-corticosteroid phosphodiesters
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, (2008/06/13)
Nucleotides of nucleosides or bases having known cytotoxic activity are reacted with steroids, preferably corticosteroids, to form corresponding cytotoxic nucleoside-corticosteroid phosphodiester analogues of the formula: STR1 wherein: steroid is the residue formed by removal of a hydroxyl hydrogen atom from a natural or synthetic adrenal corticosteroid containing the characteristic cyclopentanophenanthrene nucleus which is esterified to the phosphate moiety at the 21-position; sugar is a naturally occurring pentose or deoxypentose in the furanose form, preferably ribose, deoxyribose, lyxose, xylose or arabinose and especially ribose, deoxyribose or arabinose, which is esterified to the phosphate moiety at the 5'-position and covalently bonded to the heterocycle moiety at the 1'-position to form a nucleoside; and heterocycle is a purine, pyrimidine, hydrogenated pyrimidine, triazolopurine or similar nucleoside base. The conjugates exhibit an enhanced therapeutic index as compared to the parent nucleoside or base compounds, and are thus useful cytotoxic, antiviral and antineoplastic agents.
