10417-63-7

Basic information

• Product Name: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione
• Synonyms: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione;16α-Methyl Prednisolone;(11beta,16alpha)-11,17,21-Trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione;16alpha-Methylprednisolone
• CAS NO: 10417-63-7
• Molecular Formula: C₂₂H₃₀O₅
• Molecular Weight: 374.4706
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 10417-63-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 571.8±50.0 °C(Predicted)
• Appearance: /
• Density: 1.28±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Dioxane (Slightly), DMSO (Sparingly), Methanol (Slightly)
• PKA: 12.48±0.70(Predicted)
• CAS DataBase Reference: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione(10417-63-7)
• EPA Substance Registry System: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione(10417-63-7)

Safety Data

• Hazardous Substances Data: 10417-63-7(Hazardous Substances Data)

Usage

Uses

16α-Methylprednisolone is the 16α-Methyl analogue of Prednisolone (P703740). 16α-Methylprednisolone is an anti-inflammatory corticosteroid.

Downstream Products

• 71868-53-6 16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate 
• 10106-41-9 17α,21-dihydroxy-16α-methyl-1,4,9(11)-pregnatriene-3,20-dione 21-acetate 

Relevant articles and documents

Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid

This invention discloses an improved process for the production of corticoids from 17α-hydroxy steroids utilizing peroxymonosulfate.