10419-35-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Ethoxy-3,4-dihydro-2H-chromene is used as a pharmaceutical agent for its potential antioxidant and anti-inflammatory properties, which can contribute to the treatment of various diseases and conditions where oxidative stress and inflammation play a significant role.
Used in Antitumor Applications:
In the field of oncology, 2-ethoxy-3,4-dihydro-2H-chromene is used as an antitumor agent. Its potential to inhibit tumor growth and progression is being studied, with the aim of developing new therapeutic strategies for cancer treatment.
Used in Medicinal Chemistry Research:
2-Ethoxy-3,4-dihydro-2H-chromene serves as a subject of research in medicinal chemistry, where its diverse biological activities are explored for the development of new drugs and therapeutic agents. Its unique chemical structure and properties make it a promising candidate for further investigation and potential application in various medical fields.

Upstream product

• 4526-41-4 o-(methylthiomethyl)-phenol 
• 109-92-2 ethyl vinyl ether 
• 932-30-9 2-Hydroxybenzylamine 

Downstream Products

• 19346-79-3 o-(3-Aethoxyheptyl)-phenyl 
• 19346-77-1 o-(3-Aethoxy-pentyl)-phenol 
• 19346-80-6 o-(3-Aethoxyheptyl)-anisol 

Relevant academic research and scientific papers

Hydroxy-1-aminoindans and derivatives: Preparation, stability, and reactivity

The chemical stability and reactivity of hydroxy-1-aminoindans and their N-propargyl derivatives are strongly affected by the position of the OH group and its orientation relative to that of the amino moiety. Thus, the 4- and 6-OH regioisomers were found to be stable, while the 5-OH analogues were found to be inherently unstable as the free bases. The latter, having a para orientation between the OH and the amino moieties, could be isolated only as their hydrochloride salts. 7-Hydroxy-1-aminoindans and 7-hydroxy-1- propargylaminoindans represent an intermediate case; while sufficiently stable even as free bases, they exhibit, under certain experimental conditions, unexpected reactivity. The instability of the 5- and 7-hydroxy-aminoindans is attributed to their facile conversion to the corresponding, reactive quinone methide (QM) intermediates. The o-QM obtained from 7-hydroxy-aminoindans was successfully trapped with ethyl vinyl ether via a Diels-Alder reaction to give tricyclic acetals 32a,b.

A New Generation of o-Quinone Methides from o-(1-(Alkylthio)alkyl)phenols under Mild Conditions

o-(1-(Alkylthio)alkyl)phenols are converted into o-quinone methides in good yield by treatment with silver oxide under mild conditions.Since the methides tend to prefer (E) configuration, cis-4-alkyl-2-alkoxychromans are exclusively obtained as a result o