104211-10-1Relevant articles and documents
CHIRAL SYNTHESIS OF 3,4-DISUBSTITUTED 2-AZETIDINONES FROM (R,R)-(+)-TARTARIC ACID
Gateau-Olesker, Alice,Cleophax, Jeannine,Gero, Stephan D.
, p. 41 - 44 (1986)
A novel route is described for the enantioselective synthesis of 2-azetidinones 24 and 25 from (R,R)-(+)-tartaric acid.Monomethylation, monobenzylation of 2 and the use of site specific pig liver esterase (PLE) to produce 6 and 7 are the key steps in sequ
Synthesis of 3α-alkoxy-4β-substituted-2-azetidinones from L(+)-tartaric acid
Barton, Derek H. R.,Cleophax, Jeanine,Gateau-Olesker, Alice,Gero, Stephan D.,Tachdjian, Catherine
, p. 8381 - 8396 (2007/10/02)
Tartaric acid, regioselective saponification, Pig Liver Esterase, 3-methoxy-2-azetidinone, N-Hydroxy-2-thiopyridone, radical decarboxylation. The synthesis of 3α-alkoxy-4β-azetidinones from L(+) tartaric acid is described. Regioselective saponification and methylation along with a stereo selective radical decarboxylative alkylation are key steps leading to optically pure trans-β-lactams.
Optically active 4-carbalkoxy-2-azetidinones
-
, (2008/06/13)
Novel 2-azetidinones of the formula STR1 wherein R is alkyl of 1 to 4 carbon atoms, R1 is selected from the group consisting of hydrogen, --OH, protected hydroxy and --OCH2 --COOR', R' is selected from the group consisting of hydroge