1042159-64-7

Basic information

• Product Name: 3-(3-(dimethylamino)phenyl)-5-fluoroindolin-2-one
• Synonyms: 3-(3-(dimethylamino)phenyl)-5-fluoroindolin-2-one
• CAS NO: 1042159-64-7
• Molecular Formula: C₁₆H₁₅FN₂O
• Molecular Weight: 270
• Mol File: 1042159-64-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3-(dimethylamino)phenyl)-5-fluoroindolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-(dimethylamino)phenyl)-5-fluoroindolin-2-one(1042159-64-7)
• EPA Substance Registry System: 3-(3-(dimethylamino)phenyl)-5-fluoroindolin-2-one(1042159-64-7)

Safety Data

• Hazardous Substances Data: 1042159-64-7(Hazardous Substances Data)

Upstream product

• 56341-41-4 5-fluoroindol-2(3H)-one 
• 6848-13-1 3-chloro-N,N-dimethylaniline 

Relevant articles and documents

Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles

In the cross-coupling reactions of unprotected oxindoles with aryl halides, Pd- and Cu-based catalyst systems displayed orthogonal chemoselectivity. A Pd-dialkylbiarylphosphine-based catalyst system chemoselectively arylated oxindole at the 3 position, while arylation occurred exclusively at the nitrogen using a Cu-diamine-based catalyst system. Computational examination of the relevant L1Pd(Ar)(oxindolate) and diamine-Cu(oxindolate) species was performed to gain mechanistic insight into the controlling features of the observed chemoselectivity.