1042701-07-4Relevant articles and documents
A short total synthesis of (±)-epimeloscine and (±)-meloscine enabled by a cascade radical annulation of a divinylcyclopropane
Zhang, Hanmo,Curran, Dennis P.
, p. 10376 - 10378 (2011/08/05)
The first stereoselective synthesis of epimeloscine has been accomplished in 13 total steps with a longest linear sequence of 10 steps. The core of the synthesis takes only five steps, the key ones being acylation, stereoselective tandem radical cyclization of a divinylcyclopropane to make two rings, and group-selective ring-closing metathesis of the resulting divinylcyclopentane to make the last ring.
An expedient strategy for the synthesis of tryptamines and other heterocycles
Nicolaou,Krasovskiy, Arkady,Trepanier, Vincent E.,Chen, David Y.-K.
supporting information; experimental part, p. 4217 - 4220 (2009/03/12)
(Chemical Equation Presented) Making many from one: N-Boc-protected anilines are converted into an array of useful N-heterocycles and tryptamines through an expedient, cascade-based synthetic sequence involving ortho metalation and subsequent coupling wit
