1042728-00-6Relevant articles and documents
Synthesis and pesticidal activities of O,O- dialkyl-N-[(4-aryl)-2- thiazolyl] phosphoramidothioates
Jain, Renuka,Jain, Satish C.,Goyal, Praveen Kumar,Vajpei, Shipra
, p. 2605 - 2610 (2008/09/21)
Several fluorine-containing O,O-dialkyl-N-[(4-aryl)-2-thiazolyl] phosphoramidothoiates were synthesized as possible antifungal and insecticidal agents by treating appropriate 2-amino-4-aryl-thiazoles with O,O-dialkyl phosphorochloridothioates. The latter were obtained by the reaction of dry alcohol on thiophosphoryl chloride in the presence of sodium metal. Some of the synthesized compounds exhibited significant antifungal activity against Aspergillus species. In insecticidal activity, compounds possessing a methyl group along with fluorine exhibited enhanced effect. It was also noted that the activity increased with the size and branching of alkyl group. Copyright Taylor & Francis Group, LLC.