2524-06-3

Basic information

• Product Name: Chloridothiophosphoric acid diisopropyl ester
• Synonyms: Chloridothiophosphoric acid diisopropyl ester;Chlorophosphonothioic acid O,O-bis(1-methylethyl) ester
• CAS NO: 2524-06-3
• Molecular Formula: C₆H₁₄ClO₂PS
• Molecular Weight: 216.6659
• Mol File: 2524-06-3.mol

Chemical Properties

• Boiling Point: 230°Cat760mmHg
• Flash Point: 92.9°C
• Appearance: /
• Density: 1.174g/cm³
• Vapor Pressure: 0.102mmHg at 25°C
• Refractive Index: 1.478
• CAS DataBase Reference: Chloridothiophosphoric acid diisopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Chloridothiophosphoric acid diisopropyl ester(2524-06-3)
• EPA Substance Registry System: Chloridothiophosphoric acid diisopropyl ester(2524-06-3)

Safety Data

• Hazardous Substances Data: 2524-06-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14ClO2PS/c1-5(2)8-10(7,11)9-6(3)4/h5-6H,1-4H3

Upstream product

• 545-06-2 trichloroacetonitrile 
• 107-56-2 O,O-diisopropyl hydrogen phosphorodithioate 
• 51756-01-5 diisopropoxyphosphorylsulfenyl chloride 
• 18108-37-7 5-methyl-2-phenyl-1H-1,2,3-diazaphosphole 
• 127832-97-7 10-(N'-phenylchloroformimidoyl)phenothiazine 
• 3018-12-0 dichloroacetonitrile 
• 53310-50-2 3-chloropropyl thiocyanate 
• 3031-21-8 bis(O,O-diisopropoxyphosphinothioyl)disulfide 
• 110-82-7 cyclohexane 

Downstream Products

• 1042727-98-9 C₁₅H₂₀FN₂O₂PS₂ 
• 1042727-99-0 C₁₆H₂₂FN₂O₂PS₂ 
• 1042728-00-6 C₁₅H₁₉ClFN₂O₂PS₂ 
• 1042728-01-7 C₁₅H₁₉ClFN₂O₂PS₂ 
• 55051-32-6 (4-Phenyl-thiazol-2-yl)-thiophosphoramidic acid O,O'-diisopropyl ester 
• 1144028-83-0 N-methyl-N-diisopropoxyphosphinothioyloxy-4-chlorobenzamide 
• 128342-57-4 potassium salt of N-diisopropoxythiophosphorylthiobenzamide 
• 135309-75-0 potassium N-diisopropoxythiophosphorylthiobenzamide acetone complex 

Relevant articles and documents

Reactions of Phosphorylsulfenyl Chlorides with 2H-1,2,3-Diazaphospholes

Formation of a quasiphosphonium salt in reaction of phosphorylsulfenyl chlorides with 1,2,3-diazaphospholes was established by dynamic 31P NMR spectroscopy. The salt is formed by addition of 2 mol of phosphorylsulfenyl chloride to the σ2λ3P=C endocyclic fragment by the 1,1- and 1,2-addition schemes. Decomposition of the salt yields mainly O,O-dialkyl phosphothiochloridate and, to a lesser extent, dialkyl phosphochloridate.

SYNTHESIS OF 10-(N'-PHENYL)IMIDOYL DERIVATIVES OF PHENOTHIAZINE, AND THEIR REACTIONS WITH O,O-DIALKYLTHIO- AND DITHIOPHOSPHATES

Condensation of phenothiazine with phenyl isocyanide dichloride has given 10-(N'-phenylchloroformimidoyl)phenothiazine, exchange reactions of which with salts of dialkylthio- and dithiophosphoric acids result in rearrangement of the initially formed 10-phenothiazines to 10-thiocarbamoyl>phenothiazines, while reaction with diisopropyl dithiophosphoric acid affords diisopropyl chlorothiophosphate, phenyl isothiocyanate, and phenothiazine. 10-(N'-Phenylethoxyformimidoyl)phenothiazine alkylates dithiophosphoric acid to give 10-(N'-phenylcarbamoyl)phenothiazine, while N2-phenyl-N1,N1-diethyl-(10-phenothiazinyl)formamidine reacts with diisopropyl dithiophosphoric acid, affording the salt N2-phenyl-N1,N1-diethyl-(10-phenothiazinyl)formamidinium O,O-diisopropyl dithiophosphate.

NEW OBSERVATION ON THE CHLORINOLYSIS OF BIS-DIALKOXYTHIOPHOSPHORYL DISULFIDES

The spectroscopic and chemical evidence that the dialkoxythiophosphorylsulfenyl chlorides 5 are formed as intermediates in the chlorination of bis-dialkoxythiophosphoryl disulfides 3 is presented.Key words: Bis-dialkoxythiophosphoryl disulfides; dialkoxythiophosphorylsulfenyl chlorides; dialkylthiophosphorochloridate; 31P NMR.