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2-(TRIFLUOROMETHYL)CYCLOHEXANOL, with the systematic name 2-(trifluoromethyl)cyclohexan-1-ol, is a rare and complex aromatic compound belonging to the class of secondary alcohols. It features a cyclohexane ring, a six-membered single ring of carbon atoms, with a trifluoromethyl group and a hydroxy (alcohol) group attached. Its molecular formula is C7H11F3O, and its physical properties, such as boiling point and density, may vary depending on its purity and synthesis specifics. Due to its potential biohazardous effects, it should be handled with care.

104282-19-1

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104282-19-1 Usage

Uses

Used in Synthetic Organic Chemistry:
2-(TRIFLUOROMETHYL)CYCLOHEXANOL is used as a key intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities and materials. Its unique structure allows for versatile chemical reactions, making it a valuable component in the field of synthetic organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 104282-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,2,8 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 104282-19:
(8*1)+(7*0)+(6*4)+(5*2)+(4*8)+(3*2)+(2*1)+(1*9)=91
91 % 10 = 1
So 104282-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H11F3O/c8-7(9,10)5-3-1-2-4-6(5)11/h5-6,11H,1-4H2

104282-19-1 Well-known Company Product Price

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  • Aldrich

  • (762075)  2-(Trifluoromethyl)cyclohexanol  mixture of cis and trans isomers, 97%

  • 104282-19-1

  • 762075-1G

  • 782.73CNY

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104282-19-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(trifluoromethyl)cyclohexan-1-ol

1.2 Other means of identification

Product number -
Other names cis-,trans-2-(trifluoromethyl)cyclohexanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104282-19-1 SDS

104282-19-1Downstream Products

104282-19-1Relevant academic research and scientific papers

Photochemistry of 2-(Trifluoromethyl)cyclohexanone

Semisch, Christoph,Margaretha, Paul

, p. 664 - 668 (1984)

The photochemical behaviour of the title compound 1a is compared to that of the non-fluorinated parent ketone 2-methylcyclohexanone (1b).Substitution of the CH3-group on C(2) by a trifluoromethyl group strongly enhances 2H- and RH-reduction product formation in cyclohexane or 2-propanol and oxetane formation in the presence of 2-methylpropene as olefinic component.Under all these conditions 1b exclusively undergoes α-cleavage, a process observed for 1a only in non-reducing solvents as benzene or tert-butyl alcohol.

An improved synthesis of 2-, 3-, and 4-(trifluoromethyl)cyclohexylamines

Alekseenko, Anatoliy N.,Denis, Klukovsky,Lukin, Oleg,Mykhailiuk, Pavel K.,Shishkin, Oleg V.,Pustovit, Yurii M.

, p. 2739 - 2742 (2012/11/07)

An improved synthesis of 2-, 3-, and 4-trifluoromethylcyclohexylamines on a multigram scale via PtO2-mediated hydrogenation of the corresponding trifluoromethylanilines in trifluoroacetic acid at room temperature under atmospheric pressure is reported. The hydrogenation occurred with a remarkable stereoselectivity favoring the formation of cis-isomers. Georg Thieme Verlag Stuttgart New York.

Facile and selective alkylation of 3,3,3-trifluoropropene oxide (TFPO) with organoaluminum reagents via pentacoordinate trialkylaluminum complexes

Ooi, Takashi,Furuya, Mayumi,Maruoka, Keiji

, p. 817 - 818 (2007/10/03)

A new organoaluminum-promoted selective alkylation of 3,3,3-trifluoropropene oxide (TFPO) with several nucleophiles has been developed which involves the chelation-activated addition to fluoro epoxides via pentacoordinate trialkylaluminum complexes.

Photochemistry of 2-(Perfluoroalkyl)cycloalkanones

Semisch, Christoph,Margaretha, Paul

, p. 471 - 475 (2007/10/02)

In an earlier study we had compared the photochemical behaviour of 2-trifluoromethylcyclohexanone (1a) to that of the non fluorinated parent ketone 2-methylcyclohexanone.Substitution of the methyl group on C(2) by a CF3-group strongly enhances bimolecular reactions such as reductionproduct formation in 2-propanol or oxetane formation in the presence of alkenes.We now report preliminary results on monomolecular photochemical reactions of several 2-(perfluoroalkyl)cycloalkanones.

Trifluoromethyl derivatives of cyclohexanol and cyclohexanone and their reactions

Zalesskaya, I. M.,Blakitnyi, A. N.,Saenko, E. P.,Fialkov, Yu. A.,Yagupol'skii, L. M.

, p. 1031 - 1038 (2007/10/02)

The catalytic hydrogenation of mono- and bistrifluoromethylphenols was investigated, and the structure of the obtained trifluoromethylcyclohexanols was established.Methods were developed for the production of trifluoromethyl derivatives of caprolactam and adipic acid.

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