104286-03-5

Usage

General Description

2-(1,3-benzoxazol-2-yl)benzoic acid is a chemical compound with a molecular formula C15H9NO3. It is a derivative of benzoxazole and benzoic acid, and is commonly used in research and pharmaceutical applications as a fluorescent probe for the detection of metal ions and other analytes. 2-(1,3-benzoxazol-2-yl)benzoic acid has also shown potential as a therapeutic agent for various diseases due to its ability to target specific biological pathways. Additionally, 2-(1,3-benzoxazol-2-yl)benzoic acid has been investigated for its antimicrobial and anti-inflammatory properties, further highlighting its potential applications in various fields of chemistry and medicine.

Upstream product

• 85-44-9 phthalic anhydride 
• 95-55-6 2-amino-phenol 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant academic research and scientific papers

Microwave-assisted direct synthesis of 2-substituted benzoxazoles from carboxylic acids under catalyst and solvent-free conditions

A direct coupling of carboxylic acids with 2-aminophenol under microwave irradiation has been achieved leading to the synthesis of 2-substituted benzoxazoles under metal and solvent-free conditions. Aliphatic, aromatic and heteroaromatic carboxylic acids provide good yields. Benzoxazole formation takes place in the presence of chloro, methoxy, phenoxy, thiophenoxy, and α,β-unsaturated functionalities. In the case of dicarboxylic acids, the reaction proceeds via the formation of the corresponding anhydride with predominant formation of the mono-benzoxazole. Georg Thieme Verlag Stuttgart.

Cyclic phosphonate ester inhibitors of microsomal triglyceride transfer protein and method

Novel cyclic phosphonate ester inhibitors of MTP are provided which have the structure STR1 wherein R2, L2, A, B, L1, R1 and R5a are as set out herein. These compounds are useful in lowering serum cho