104291-45-4Relevant academic research and scientific papers
A Facile Synthesis of Substituted Perhydro-1,3-thiazin-4-ones and 2-Thioxoperhydro-4-pyrimidinones
Elghandour, Ahmed Hafez Hussien,Ramiz, Mahmoud Mohamed Mahfouz,Ghozlan, Said Ahmed Soliman,Elmoghayar, Mohamed Riffat Hamza
, p. 983 - 988 (2007/10/02)
Depending on the reaction conditions either 2,6-disubstituted 2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones 4 or 1,6-disubstituted 2-thiouracils 5 are readily prepared by base-catalyzed cyclization of N-propenoylthioureas 3.Compounds 5 could also be obtained by Dimroth-type rearrangement of 1,3-thiazin-4-ones 4 under the same reaction conditions.
A NEW METHOD FOR PREPARATION OF 1-(4-SUBSTITUTED PHENYL)-6-PHENYL-2-THIOURACILS via CYCLIZATION OF N-(4-SUBSTITUTED PHENYL)-N'-3-PHENYLPROPENOYLTHIOUREAS AND DIMROTH REARRANGEMENT OF 2-(4-SUBSTITUTED PHENYLIMINO)-6-PHENYL-5,6-DIHYDRO-4H-1,3-THIAZIN-4-ONES
Dzurilla, Milan,Kutschy, Peter,Koscik, Dusan
, p. 2260 - 2265 (2007/10/02)
N-(4-Substituted phenyl)-N'-3-phenylpropenoylthioureas treted with lithium hydride afforded 1-(4-substituted phenyl)-6-phenyl-2-thiouracils; these could also be obtained by Dimroth rearrangement of 2-(4-substituted phenylimino)-6-phenyl-5,6-dihydro-4H-1,3
A New, Convenient Synthesis of 1,6-Diaryl-2-thioxoperhydro-4-pyrimidinones: Reaction of 3-Phenyl-2-propenoyl Isothiocyanate With Aromatic and Heteroaromatic Amines
Hafez, Ebtisam Abdal Aziz,Elmoghayar, Mohamed Rifaat Hamza,Ramiz, Mahmoud Mohamed Mahfouz
, p. 65 - 68 (2007/10/02)
The substituted thioureas 3a-h, prepared from 3-phenyl-2-propenoyl isothiocyanate (1) and aromatic or heteroaromatic amines 2a-h, cyclize in the presence of sodium ethoxide to give the perhydropyrimidine derivatives 5a-c.
A Novel Synthesis of Perhydrpyrimidine-2-thiones
Gohar, Abdel-Kerim M. N.,Abdel-Latif, F. F.,Regaila, H. A. A.
, p. 767 - 768 (2007/10/02)
Cinnamoyl isothiocyanate (1) reacts with amines (aniline, p-toluidine, benzylamine) to give the corresponding cinnamoylthiourea derivatives (2a-c).Compounds 2a-c undergo cyclization when refluxed with sodium ethoxide solution to give the corresponding per
