78374-84-2

Upstream product

• 102-92-1 cinnamoyl chloride 
• 62-53-3 aniline 
• 19495-08-0 cinnamoyl isothiocyanate 

Downstream Products

• 148931-39-9 N-cinnamoyl-N'-phenyl-urea 
• 38771-64-1 2-anilino-5-benzylidene-thiazol-4-one 
• 104291-45-4 2,3,5,6-tetrahydro-1,6-diphenyl-2-thioxo-4(1H)-pyrimidinone 
• 104721-27-9 2,3,5,6-tetrahydro-6-phenyl-2-phenylimino-4H-1,3-thiazin-4-one 
• 104721-27-9 6-Phenyl-2-phenylamino-5,6-dihydro-[1,3]thiazin-4-one 
• 107399-78-0 1,6-Diphenyl-dihydro-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Synthesis of benzoyl-N-phenylthioureas under microwave irradiation and phase transfer catalysis conditions

A simple, rapid and efficient method for the synthesis of benzoyl-N-phenylthioureas under microwave irradiation is reported. The effect of microwave irradiation power, times and phase transfer catalyst on the reaction is investigated.

A New, Convenient Synthesis of 1,6-Diaryl-2-thioxoperhydro-4-pyrimidinones: Reaction of 3-Phenyl-2-propenoyl Isothiocyanate With Aromatic and Heteroaromatic Amines

The substituted thioureas 3a-h, prepared from 3-phenyl-2-propenoyl isothiocyanate (1) and aromatic or heteroaromatic amines 2a-h, cyclize in the presence of sodium ethoxide to give the perhydropyrimidine derivatives 5a-c.

A Novel Synthesis of Perhydrpyrimidine-2-thiones

Cinnamoyl isothiocyanate (1) reacts with amines (aniline, p-toluidine, benzylamine) to give the corresponding cinnamoylthiourea derivatives (2a-c).Compounds 2a-c undergo cyclization when refluxed with sodium ethoxide solution to give the corresponding per