104295-62-7

Basic information

• Product Name: ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE
• Synonyms: ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE;Ethyl 3-(2-furyl)-1-methyl-1H-pyrazole-5-carboxylate 97%;Ethyl 3-(furan-2-yl)-1-methyl-1H-pyrazol-5-carboxylate
• CAS NO: 104295-62-7
• Molecular Formula: C11H12N2O3
• Molecular Weight: 220.22
• Mol File: 104295-62-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 57-58.5
• Boiling Point: 352.4°Cat760mmHg
• Flash Point: 166.9°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 3.85E-05mmHg at 25°C
• Refractive Index: 1.575
• PKA: -0.10±0.10(Predicted)
• CAS DataBase Reference: ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(104295-62-7)
• EPA Substance Registry System: ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE(104295-62-7)

Safety Data

• Hazardous Substances Data: 104295-62-7(Hazardous Substances Data)

Usage

General Description

Ethyl 3-(2-furyl)-1-methyl-1H-pyrazole-5-carboxylate is a chemical compound with the molecular formula C13H14N2O3. It is a furan derivative with a pyrazole ring and an ethyl ester group. ETHYL 3-(2-FURYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE has various potential applications in the fields of pharmaceuticals and agrochemicals due to its diverse pharmacological and biological activities. It is used as a building block in the synthesis of various pharmaceutical compounds and agrochemical products. Additionally, it exhibits potential antioxidant, anti-inflammatory, and antitumor properties, making it a subject of interest for further research and development. Overall, ethyl 3-(2-furyl)-1-methyl-1H-pyrazole-5-carboxylate is a versatile compound with potential applications in various industries.

InChI:InChI=1/C11H12N2O3/c1-3-15-11(14)9-7-8(12-13(9)2)10-5-4-6-16-10/h4-7H,3H2,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 34020-22-9 ethyl 5-(furan-2-yl)-1H-pyrazole-3-carboxylate 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 412304-91-7 ethyl 4-(2-furyl)-2,4-dioxobutanoate 
• 60-34-4 methylhydrazine 
• 36983-35-4 ethyl 4-(furan-2-yl)-2,4-dioxobutyrate 

Downstream Products

• 106166-52-3 5-[2]furyl-1-phenyl-1H-pyrazole 
• 100537-55-1 5-[2]furyl-1-phenyl-1H-pyrazole-3-carboxylic acid 

Relevant articles and documents

Synthesis of fluorinated and nonfluorinated tebufenpyrad analogues for the study of anti-angiogenesis MOA

In this contribution we report the synthesis of fluorinated and nonfluorinated tebufenpyrad analogues to explore potential druglike properties through the phenotypic screening as part of the Lilly Open Innovation Drug Discovery (OIDD) program.

Synthesis of new fluorinated tebufenpyrad analogs with acaricidal activity through regioselective pyrazole formation

(Chemical Equation Presented) In previous studies, our group has shown that the use of fluorinated alcohols such as trifluoroethanol (TFE) and hexafluoroisopropanol (HFIP) as solvents dramatically increases the regioselectivity in the pyrazole formation from 1,3-diketone with methylhydrazine. We have now applied this synthetic method to the preparation of new fluorinated pyrazoles, which have then been used as synthetic intermediates in the preparation of fluorinated analogs of Tebufenpyrad, a commercial acaricide. These compounds display a strong acaricidal activity that is either comparable to or better than that of the commercial compound.