10431-84-2

Basic information

• Product Name: 4,5-dihydro-2-undecyl-Oxazol
• Synonyms: 4,5-dihydro-2-undecyl-Oxazol;Oxazole,4,5-dihydro-2-undecyl-
• CAS NO: 10431-84-2
• Molecular Formula: C14H27 N O
• Molecular Weight: 225.37
• Mol File: 10431-84-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 302.5°Cat760mmHg
• Flash Point: 102.9°C
• Appearance: /
• Density: 0.93g/cm³
• Vapor Pressure: 0.00177mmHg at 25°C
• Refractive Index: 1.485
• CAS DataBase Reference: 4,5-dihydro-2-undecyl-Oxazol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydro-2-undecyl-Oxazol(10431-84-2)
• EPA Substance Registry System: 4,5-dihydro-2-undecyl-Oxazol(10431-84-2)

Safety Data

• Hazardous Substances Data: 10431-84-2(Hazardous Substances Data)

Usage

General Description

4,5-dihydro-2-undecyl-oxazol, also known as DHUO, is a chemical compound belonging to the oxazoles class. It is a yellow liquid with a molecular formula of C15H29NO, and is primarily used in the production of coatings, adhesives, and sealants. DHUO is considered to be a skin and eye irritant, and exposure to high concentrations can cause respiratory irritation and central nervous system effects. The compound is not classified as a carcinogen, mutagen, teratogen, or reproductive toxin, and there is limited evidence of its potential environmental impact. DHUO is typically handled and used with caution in industrial applications, and appropriate safety measures should be taken to minimize exposure and potential health risks.

InChI:InChI=1/C14H27NO/c1-2-3-4-5-6-7-8-9-10-11-14-15-12-13-16-14/h2-13H2,1H3

Upstream product

• 1943-83-5 2-chloroethyl isothiocyanate 
• 143-07-7 lauric acid 
• 142-78-9 N-(2-hydroxyethyl)dodecanamide 

Downstream Products

• 63451-19-4 N-(2-(Diethylamino)ethyl)dodecylamide 
• 14037-25-3 2-(1-phenylcarbamoyl-undecylidene)-oxazolidine-3-carboxylic acid anilide 

Relevant articles and documents

Facile one-pot synthesis of 2-oxazoline

We developed a facile one-pot synthesis of 2-oxazolines from carboxylic acid and 2-chloroethyl isocyanate, involving amide bond formation and a following intramolecular cyclization using 4-dimethylaminopyridine as the catalyst. A large variety of functional groups are well tolerated by the mild reaction conditions to afford diverse 2-oxazolines in good to excellent yields. This reaction will keep the chirality of the isocyanate at position 1, the R2 substituted carbon. Microwave-assisted synthesis can further enhance the reaction yield and reduce the reaction time to 5 min. This method facilities the synthesis of 2-oxazolines for diverse applications, such as 2-oxazoline derived polymers and materials.

A facile synthesis of 2-oxazolines using a PPh3-DDQ system

A facile and efficient synthesis of 2-oxazolines from N-(2-hydroxyethyl)amides using a triphenylphosphine-2,3-dichloro-5,6-dicyanobenzoquinone (PPh3-DQQ) system is described. The reaction proceeds under neutral and mild conditions, and excellent yields are obtained.

Compositions and method comprising heterocyclic compounds containing two heteroatoms as membrane penetration enhancers

A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for local or systemic use, comprising a therapeutically effective amount of a pharmaceutically active agent and a non-toxic, effective amount of penetration enhancing agent of the formula I: STR1 wherein R is a saturated or unsaturated, straight or branched, cyclic or acyclic hydrocarbon group with from 1 to 19 carbon atoms, alkoxyalkyl, haloalkyl, specifically trifluoromethyl, alkoxy, amino, alkylamino and acylamino; R' and R" are hydrogen, alkyl, trifluoromethyl, alkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, carboxy, carbalkoxy, hydroxyalkyl or lower alkyl ester thereof; X is O or NR1 wherein R1 is hydrogen, alkyl, alkenyl, alkoxyalkyl, carbalkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, hydroxyalkyl or hydroxyalkyloxyalkyl and lower alkyl ester thereof; and n is 2 or 3 are disclosed.