10432-26-5Relevant academic research and scientific papers
One-step synthesis of polysubstituted benzene derivatives by multi-component cyclization of α-bromoacetate, malononitrile and aromatic aldehydes
Yan, Chao Guo,Song, Xiao Kai,Wang, Qi Fang,Sun, Jing,Siemeling, Ulrich,Bruhn, Clemens
, p. 1440 - 1442 (2008)
Polysubstituted benzene derivatives with an unprecedented substitution pattern are produced in a novel one-pot multi-component cyclization reaction from pyridine, ethyl α-bromoacetate, malononitrile and aromatic aldehyde in refluxing acetonitrile. The Royal Society of Chemistry.
