10432-47-0Relevant academic research and scientific papers
Electrochemical transformation of malononitrile and carbonyl compounds into functionally substituted cyclopropanes: Electrocatalytic variant of the Wideqvist reaction
Elinson, Michail N.,Feducovich, Sergey K.,Lizunova, Tatiana L.,Nikishin, Gennady I.
, p. 3063 - 3069 (2007/10/03)
Electrolysis of malononitrile and carbonyl compounds in the presence of alkali metal halides in an undivided cell results in the formation of substituted 1,1,2,2-tetracyanocyclopropanes in 60-90% yield. This electrocatalytic variant of the Wideqvist reaction using malononitrile instead of bromomalonitrile was successfully performed. Electrocatalytic transformation of substituted 1,1,2,2-tetracyanocyclopropanes in methanol or ethanol in an undivided cell leads to substituted 2-amino-4,4-dialkoxy-1,5- dicyano-3-azabicyclo[3.1.0]hex-2-enes in 70-95% yields after 0.05-0.10 F/mol of electricity has been passed. (C) 2000 Elsevier Science Ltd.
Cyclopropanation of Electron-deficient Alkenes and Wideqvist-type Synthesis of Cyclopropanes mediated by Indium Metal
Araki, Shuki,Butsugan, Yasuo
, p. 1286 - 1287 (2007/10/02)
Cyclopropanation of electron-deficient alkenes and Wideqvist-type transformation of carbonyl compounds to cyclopropanes have been achieved by the action of active methylene dibromides and metallic indium.
