104331-18-2Relevant academic research and scientific papers
High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations
Ramachary, Dhevalapally B.,Narayana, Vidadala V.,Prasad, M. Shiva,Ramakumar, Kinthada
supporting information; scheme or table, p. 3372 - 3378 (2010/01/06)
An efficient amine-/ruthenium-catalyzed three-step process for the synthesis of Nefopam analogues was achieved through combinations of cascade enamine amination/iso-aromatization/allylation and diene or enyne metathesis as key steps starting from functionalized Hagemann's esters. In this communication, we discovered the application of ruthenium-catalysis on olefins containing free amines without in situ formation of salts.
The Chemistry of Aryl-lead(IV) Tricarboxylates. Reaction with Vinylogousβ-keto Esters
Ackland, Darren J.,Pinhey, John T.
, p. 2689 - 2694 (2007/10/02)
A study of the arylation of ethyl 4-oxocyclohex-2-enecarboxylate and a number of its derivatives by aryl-lead triacetates has been carried out.Ethyl 2-methyl-4-oxocyclohex-2-enecarboxylate (Hagemann's ester) (7), and ethyl 4-oxocyclohex-2-enecarboxylate (
USE OF THE ELECTROPHILIC C-ARYLATION BY ARYLLEAD TRIACETATES IN THE CONSTRUCTION OF SYNTHONS FOR AIZOACEAE AND AMARYLLIDACEAE ALKALOID SYNTHESIS
Ackland, Darren J.,Pinhey, John T.
, p. 5331 - 5334 (2007/10/02)
The vinylogous β-keto esters, ethyl 2-methyl-4-oxocyclohex-2-ene-carboxylate (Hagemann's Ester) (4), ethyl 4-oxocyclohex-1-ene-carboxylate (7a) and its double bond isomer (7b), undergo regiospecific arylation with aryllead triacetates at C1; reaction of t
