104358-48-7

Basic information

• Product Name: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-(3-methylbut-2-en-1-yl)phenol
• Synonyms: 4-((1E)-3-Hydroxy-1-propenyl)-2-(3-methyl-2-butenyl)phenol; Phenol, 4-((1E)-3-hydroxy-1-propenyl)-2-(3-methyl-2-butenyl)-; phenol, 4-[(1E)-3-hydroxy-1-propen-1-yl]-2-(3-methyl-2-buten-1-yl)-
• CAS NO: 104358-48-7
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.2915
• Mol File: 104358-48-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 377.2°C at 760 mmHg
• Flash Point: 178.6°C
• Density: 1.08g/cm³
• Vapor Pressure: 2.33E-06mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-(3-methylbut-2-en-1-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-(3-methylbut-2-en-1-yl)phenol(104358-48-7)
• EPA Substance Registry System: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-(3-methylbut-2-en-1-yl)phenol(104358-48-7)

Safety Data

• Hazardous Substances Data: 104358-48-7(Hazardous Substances Data)

Upstream product

• 3943-97-3 methyl 4-hydroxycinnamate 
• 7400-08-0 p-Coumaric Acid 
• 72704-01-9 (E)-methyl 3-[4-Hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]acrylate 

Relevant articles and documents

Structure-antimutagenic activity relationship study of plicatin B

A systematic structure-activity relationship study of plicatin B (1), an antimutagenic constituent of Psoralea juncea, was undertaken with a view toward elucidating its chemical mode of action and possibly optimizing its antimutagenic activity during the process. Compound 1 and its related analogues were examined for their antimutagenic activity against mutations induced by ethyl methanesulfonate, a direct acting mutagen and alkylating agent, in Salmonella typhimurium strain TA100, utilizing the modified Ames test protocol. The dihydro analogue 3 resulting from saturation of the conjugated alkene double bond of 1 was found to exhibit reduced cytotoxicity and enhanced efficacy relative to the parent compound. This result serves preliminarily to exclude a Michael acceptor role of the α,β-unsaturated carbonyl moiety in connection with its antimutagenic activity.