1043601-50-8 Usage
General Description
1H-Indole-3-carbonitrile, 7-bromo- is a chemical compound with the molecular formula C9H6BrN. It is a derivative of indole, a heterocyclic organic compound. The presence of a bromine atom at the 7-position of the indole ring gives this compound unique properties and potential applications in various fields. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. The compound has been studied for its potential biological activities, including its role as an antagonist of the 5-HT6 receptor, which makes it a potential candidate for the treatment of neurological disorders. Additionally, the presence of a nitrile functional group in the molecule makes it a potential precursor for the synthesis of various other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1043601-50-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,3,6,0 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1043601-50:
(9*1)+(8*0)+(7*4)+(6*3)+(5*6)+(4*0)+(3*1)+(2*5)+(1*0)=98
98 % 10 = 8
So 1043601-50-8 is a valid CAS Registry Number.
InChI:InChI=1S/C9H5BrN2/c10-8-3-1-2-7-6(4-11)5-12-9(7)8/h1-3,5,12H
1043601-50-8Relevant articles and documents
GaCl3-Catalyzed C-H Cyanation of Indoles with N-Cyanosuccinimide
Wang, Xue,Makha, Mohamed,Chen, Shu-Wei,Zheng, Huaiji,Li, Yuehui
, p. 6199 - 6206 (2019)
An efficient GaCl3-catalyzed direct cyanation of indoles and pyrroles using bench-stable electrophilic cyanating agent N-cyanosuccinimide was achieved and afforded 3-cyanoindoles and 2-cyanopyrroles in good yields and excellent regioselectivities. Notably, this protocol exhibited high reactivity for unprotected indoles and was applicable to a broad range of indole and pyrrole substrates.
