104371-51-9

Usage

Uses

Used in Pharmaceutical Industry:
Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester is used as a key component in the development of antibiotics targeting bacterial cell walls. Its role in the peptidoglycan structure makes it a potential target for new antimicrobial agents, as disrupting the synthesis or function of Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester can lead to the weakening or destruction of bacterial cell walls, ultimately killing the bacteria.
Used in Research and Development:
In the field of microbiology and biochemistry, Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester is used as a research tool to study the structure, function, and biosynthesis of peptidoglycan in bacterial cell walls. Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester can help scientists better understand the mechanisms underlying bacterial growth, division, and resistance to antibiotics, leading to the development of more effective treatments for bacterial infections.
Used in Drug Delivery Systems:
Similar to gallotannin, Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester can be employed in the development of novel drug delivery systems to improve the efficacy and bioavailability of antibiotics. By incorporating Benzyl N-Acetyl-4,6-O-benzylidene-α-D-muramic Acid, Methyl Ester into nanoparticles or other carriers, researchers can potentially enhance the delivery of antibiotics to target bacterial cells, increasing their therapeutic effectiveness and reducing the likelihood of resistance development.

InChI:InChI=1/C26H31NO8/c1-16(24(29)30-3)33-23-21(27-17(2)28)26(31-14-18-10-6-4-7-11-18)34-20-15-32-25(35-22(20)23)19-12-8-5-9-13-19/h4-13,16,20-23,25-26H,14-15H2,1-3H3,(H,27,28)/t16-,20?,21+,22-,23-,25?,26+/m1/s1

Upstream product

• 186581-53-3 diazomethane 
• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 
• 13343-62-9 benzyl 2-acetamido-2-deoxy-α-D-glucopyranoside 
• 100-51-6 benzyl alcohol 
• 13343-63-0 benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 598-78-7 (R,S)-2-chloropropionic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 39524-03-3 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(S)-1-carboxyethyl>-α-D-glucopyranoside, Na salt 
• 104303-53-9 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside, Na salt 
• 72009-73-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside, HONB ester 
• 259100-10-2 N-{2-O-[butyl 2-acetamido-2,3-dideoxy-4,6-O-isopropylidene-β-D-glucopyranosid-3-yl]-D-lactoyl}-L-alanyl-D-isoglutamine benzyl ester 
• 172986-19-5 (R)-4-{(S)-2-[(R)-2-((2R,3R,4R,5S,6R)-3-Acetylamino-2-butoxy-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester 
• 81629-37-0 benzyl 2-acetamido-4,6-di-O-acetyl-2-deoxy-3-O-<(R)-1-(methoxycarbonyl)ethyl>-α-D-glucopyranoside 
• 730911-70-3 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(S)-1-carboxyethyl>-α-D-glucopyranoside 
• 40269-09-8 benzyl 2-acetamido-2-deoxy-3-O-<(R)-1-(methoxycarbonyl)ethyl>-α-D-glucopyranoside 
• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 
• 15008-41-0 benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(D-1-carboxyethyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of α and β anomers of UDP-N-acetylmuramic acid

A convenient synthesis of UDP-N-acetylmuramic acid, a key compound for the study of the cytoplasmic synthetases of bacterial peptidoglycan, is described. Separation of its two anomers was carried out by HPLC. The α anomer is identical with natural UDP-N-a

The synthesis and biological activities of anomeric butyl glycosides of muramyl dipeptide

The synthesis of anomeric butyl glycosides of muramyl dipeptide was reported. α-Butyl glycoside of N-acetyl-D-glucosamine was 3-O-benzylidenated and the benzylidene derivative was 3-O-alkylated by the Williamson reaction with sodium (S)-2-chloropropionate