81629-37-0Relevant academic research and scientific papers
The synthesis and biological activities of anomeric butyl glycosides of muramyl dipeptide
Pertel,Kadun,Kakayan,Chirva,Krivorutchenko,Krivoshein,Bakova,Andronovskaya
, p. 628 - 634 (2007/10/03)
The synthesis of anomeric butyl glycosides of muramyl dipeptide was reported. α-Butyl glycoside of N-acetyl-D-glucosamine was 3-O-benzylidenated and the benzylidene derivative was 3-O-alkylated by the Williamson reaction with sodium (S)-2-chloropropionate
METHANOLYSIS AND AMINOLYSIS OF N-ACETYLMURAMIC ACID LACTONES: EVIDENCE FOR THE RETENTION OF THE D-gluco CONFIGURATION
Keglevic, Dina,Pongracic, Mario
, p. 85 - 100 (2007/10/02)
Methanolysis of benzyl α-glycosides of N-acetylmuramic acid lactones with HO-6 free (2) and substituted (4, 7, 10, and 12) is catalysed by small amounts of silica gel to give, exclusively, the corresponding methyl esters with HO-4 unsubstituted (3, 5, 8,
Synthesis of carbohydrate analogs (positional, configurational, and optical) of n-acetylmuramoyl-L-alanyl-D-isoglutamine, and their immunoadjuvant activities.
Hasegawa,Kaneda,Goh,Nishibori,Kiso,Azuma
, p. 143 - 163 (2007/10/02)
2-Acetamido-2-deoxy-4- and -6-O-(D-2-propanoyl-L-alanyl-D-isoglutamine)-D-glucopyranose, 2-acetamido-2-deoxy-3-O-(D-2-propanoyl-L-alanyl-D-isoglutamine)-D-allopyranose, -D-gulopyranose, -D-galactopyranose, -D-mannopyranose, and -L-idopyranose, and 3-O-(D-2-propanoyl-L-alanyl-D-isoglutamine)-D- and -L-glucopyranose were synthesized, in order to clarify the structural requirements for the immunoadjuvant activity of the carbohydrate moiety in N-acetylmuramoyl-L-alanyl-D-isoglutamine. Immunoadjuvant activity of the N-acetylmuramoyl-dipeptide analogs was examined in guinea-pigs.
