1043904-24-0Relevant articles and documents
Microwave-assisted simple synthesis of substituted 4-quinolone derivatives
Cao, Xin,You, Qi-Dong,Li, Zhi-Yu,Yang, Yan,Wang, Xiao-Jian
experimental part, p. 4375 - 4383 (2010/05/01)
A simple and efficient method was developed for the synthesis of 4-quinolone-3-carboxylic esters and 4-quinolone-3-carbonitriles under microwave (MW) activation using anilines and acrylates as materials. All reactions demonstrated the benefits of microwave reactions: convenient operation, short reaction time, and good yields.
Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase
Cao, Xin,You, Qi-Dong,Li, Zhi-Yu,Guo, Qing-Long,Shang, Jing,Yan, Ming,Chern, Ji-Wang,Chen, Men-Ling
, p. 5890 - 5898 (2008/12/21)
Because both c-Src and iNOS are key regulatory enzymes in tumorigenesis, a new series of 4-heteroarylamino-3-quinolinecarbonitriles as potent dual inhibitors of both enzymes were designed, prepared, and evaluated for blocking multiple signaling pathways i
