1043906-47-3Relevant articles and documents
Efficient synthesis of monosubstituted 3-alkynylfurans via Suzuki coupling
Yang, Xiaobao,Zhu, Li,Zhou, Yuedong,Li, Zhong,Zhai, Hongbin
, p. 1729 - 1732 (2008/12/22)
A convenient synthesis of monosubstituted 3-alkynyl-furans by Suzuki coupling reaction of 3-furanylboronic acid with substituted acetylene bromides is described. The internal alkyne products were attainable in 50-89% yields from substrates free of relatively acidic protons. Our protocol is expected to find applications in the synthesis of structurally related natural products.