104416-18-4

Upstream product

• 104416-15-1 3-(4-p-terphenylyl)-3-oxopropanenitrile 
• 100-52-7 benzaldehyde 
• 5171-64-2 1-[1,1';4',1'']terphenyl-4-yl-ethanone 
• 104416-14-0 5-(4-p-terphenylyl)isoxazole 
• 104416-13-9 3-dimethylamino-1-(4-p-terphenylyl)-2-propen-1-one 
• 104416-16-2 2-benzylidene-3-(4-p-terphenylyl)-3-oxopropanenitrile 

Relevant academic research and scientific papers

SYNTHESIS OF 3,5-DICYANO-4-PHENYL-2,6-BIS(4-p-TERPHENYLYL)-1,4-DIHYDROPYRIDINE. AN ATTEMPT AT EXTENDING THE HANTZSCH SYNTHESIS

The 3-oxopropanenitrile IIIc, prepared from 4-acetyl-p-terphenyl (IV) by the sequence IV -> V -> VI -> IIIc, reacts with benzaldehyde and ammonium acetate in acetic acid to give the Hantzsch dihydropyridine VIIc and the corresponding pyridine derivative VIIIc.The alternative cyclocondensation of benzylidene derivative IIc and 3-oxopropanenitrile IIIc in the presence of ammonium acetate exclusively gives the pyridine derivative VIIIc.Rate of thermal and oxidative aromatizations of the 1,4-dihydropyridine derivatives, VIIa-VIIc -> VIIIa-VIIIc, decreases in the order VIIc > VIIb > VIIa.Mechanism of these transformations and spectral characteristics of compounds VIIc and VIIIc are discussed with regard to their molecular structure.