104416-45-7Relevant academic research and scientific papers
Hydroxymethylation of 2-Hydroxypropiophenones in Aqueous Medium: Synthesis of 3-Hydroxymethyl-3-methyl-4-chromanones and Their Conversion to 3-Methyl-4-chromanone-3-acetic Acids
Barlocco, Daniela,Cignarella, Giorgio,Curzu, Maria Michela
, p. 876 - 878 (1985)
Reaction of o-hydroxypropiophenone (1a) with aqueous formaldehyde in sodium hydroxide solution led to the mono-hydroxymethylated 2a and/or the bis-hydroxymethylated derivative 3a, as well as to 3-methyl-4-chromanone (4a) and/or 3-methyl-3-hydroxymethyl-4-
