1044200-45-4Relevant academic research and scientific papers
Performance of C1-symmetric chiral ammonium betaines as catalysts for the enantioselective Mannich-type reaction of α- nitrocarboxylates
Uraguchi, Daisuke,Koshimoto, Kyohei,Sanada, Chisato,Ooi, Takashi
, p. 1189 - 1190 (2010)
The catalytic performance of C1-symmetric chiral ammonium betaines in the enantioselective direct Mannich-type reaction of α-nitrocarboxylates with N-Boc imines has been investigated. The most effective catalyst structure has been identified; this provides a reliable synthetic route to a variety of enantiomerically enriched α- tetrasubstituted α,β-diamino acid derivatives.
