1044256-89-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-chlorobenzyl bromide is used as a reagent for the preparation of biologically active molecules, specifically for the development of antiviral and antitumor agents. Its unique functional group allows for the creation of new compounds with potential therapeutic applications.
Used in Agricultural Chemicals Industry:
3-Bromo-2-chlorobeznyl bromide is utilized in the manufacture of agricultural chemicals, where its reactivity and functional group contribute to the production of effective products for crop protection and enhancement of agricultural yields.
Used in Dye Industry:
3-Bromo-2-chlorobenzyl bromide is employed in the synthesis of dyes, leveraging its chemical properties to produce a range of colorants for various applications, including textiles, plastics, and printing inks.
Used in Specialty Chemicals Industry:
3-Bromo-2-chlorobeznyl bromide finds application in the production of specialty chemicals, where its unique characteristics are harnessed to create high-value products for niche markets, such as fragrances, flavorings, and advanced materials.

Upstream product

• 7463-35-6 N-(3-chloro-2-methylphenyl)acetamide 
• 627531-47-9 4-amino-2-chloro-3-methylbromobenzene 
• 125328-80-5 N-(4-bromo-3-chloro-2-methylphenyl)acetamide 
• 1261524-75-7 (3-bromo-2-chloro-phenyl)methanol 
• 56961-27-4 3-bromo-2-chloro-benzoic acid 
• 97329-43-6 1-bromo-2-chloro-3-methyl-benzene 

Downstream Products

• 1256558-18-5 2-{[(3-bromo-2-chlorophenyl)methyl]sulfanyl}-6-methylpyrimidin-4-ol 

Relevant academic research and scientific papers

Novel biphenyl derivative as well as preparation method and medical application thereof

The invention relates to the field of medicinal chemistry, and discloses biphenyl derivatives with PD-1/PD-L1 inhibitory activity as well as a preparation method and application of the biphenyl derivatives. The invention further discloses a composition containing the biphenyl derivative with the PD-1/PD-L1 inhibitory activity or the pharmaceutically acceptable salt of the biphenyl derivative and a pharmaceutically acceptable carrier of the biphenyl derivative, and application of the biphenyl derivative in preparation of a PD-1/PD-L1 inhibitor. The compound can be used for treating tumors.

Biphenyl compound as well as preparation method and medical application thereof

The invention discloses a biphenyl compound as well as a preparation method and medical application thereof, the structure of the biphenyl compound is shown as a formula (I) or a formula (II), and thebiphenyl compound or pharmaceutically acceptable salt, tautomer, meso-isomer, raceme, stereoisomer, metabolite, metabolite precursor, prodrug or solvate thereof is a PD-L1 inhibitor. The compound hasa remarkable inhibiting effect on the interaction of PD-1 and PD-L1 protein, so that the compound can be applied to the preparation of PD-L1 inhibitors and immunomodulator drugs for preventing or treating tumors, autoimmune diseases, organ transplant rejection, infectious diseases and inflammatory diseases.

Novel phenanthrene compounds, a method of making the same and organic electronic devices using the same

The present invention relates to novel phenanthrene compounds having excellent luminous efficiency and lifespan, a manufacturing method thereof, and an organic electronic device including the novel phenanthrene compounds. The novel phenanthrene compounds according to the present invention can form steric conformation, can improve performance through improvement of electronic density, also can improve performance by regulating the molecular weight and position of a functional group because the molecular weight of the compounds is low, and can minutely regulate luminous wavelength and improve performance according to types of the functional groups. As the result, the organic electronic device including the novel phenanthrene compounds has high brightness, excellent thermal resistance, long lifespan, and high efficiency.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.

ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS

The invention provides well-defined aryl fluoroethyl ureas that are useful as selective alpha2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of alpha2 adrenergic receptors.

Quinolinone derivaties and uses thereof

The invention provides compounds of the formula: and pharmaceutically acceptable salts or prodrugs thereof, wherein m, p, q, r, A, E, X, Y, R1, R4, R5, R6, R7, R8, R9 and are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I.